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To establish a method for calling digital karyotypes using the Illumina HumanCoreExome BeadChip, we calculated the percent of cells within a population that were required to detect a chromosome alteration. We performed serial dilutions of an iPSC line with Trisomy 12, 13, 14, 17, 20, and XXY and a g...
ORGANISM(S): Homo sapiens 
Our understanding of Alzheimer’s disease (AD) pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model the sporadic form of AD. It may be possible to overcome these challenges by reprogramming primary cells from patients into induced plurip...
ORGANISM(S): Homo sapiens 
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