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ProteomicsProtective effects of breviscapine on HFHC diet-induced C57 mice
The phosphorylomics data of liver tissue of 16-week-old HFHC-induced mice treated with saline or breviscapine for 8 weeks. The mice fed with high fat and high cholesterol were also divided into two groups. The control group was treated with normal saline for 8W, and the drug group was treated with b...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD029975 | Pride
Mouse Phosphorylomics Liver 
GenomicsscRNAseq and TCRseq of hepatic and splenic CD8T cells from normal diet fed (ND), HFHC diet fed (HFHC), and resolution induced (RES) mice.
scRNAseq and TCRseq of hepatic and splenic CD8T cells from normal diet fed (ND), HFHC diet fed (HFHC), and resolution induced (RES) mice.
PRJNA735386 | ENA
ProteomicsProtective effects of breviscapine on HFHC diet-induced C57 mice
The proteomics data of liver tissue of 16-week-old HFHC-induced mice treated with saline or breviscapine for 8 weeks. The mice fed with high fat and high cholesterol were also divided into two groups. The control group was treated with normal saline for 8W, and the drug group was treated with brevis...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD029867 | Pride
Mouse Hfhc diet 
TranscriptomicsscRNAseq and TCRseq of hepatic and splenic CD8T cells from normal diet fed (ND), HFHC diet fed (HFHC), and resolution induced (RES) mice.
To explore key features associated with the resolution process in liver fibrosis, we here applied a unique murine model, in which mice were fed HFHC diet for 24 weeks, and then continued with the HFHC diet (HFHC) or switched to a normal diet (RES) for 5 weeks. We noted that both the frequency and nu...
ORGANISM(S): Mus musculus 
2021-06-11 | GSE176210 | GEO
TranscriptomicsRegulation of glycolytic activity in multiple cell types explains the ability of FDG-PET to measure disease activity in atherosclerosis
The aim of the single cell RNASeq experiment is to explore the molecular changes in the progressing and regressing plaques of an atherosclerosis pig mode and specifically the long-term changes glycolysis pathway. To produce these glycolysis signatures, we randomized male and female pigs into two exp...
ORGANISM(S): Sus scrofa 
2025-07-09 | E-MTAB-13898 | biostudies-arrayexpress
TranscriptomicsChanges of hepatic gene expression in C57BL/6N male mice fed high-fat high-calorie fructose (HFHC) diet for 8 weeks
In murine NAFL/NASH models, high-fat high-calorie fructose (HFHC) diet fed for 16 weeks induces hepatic steatosis, inflammatory cells infilatration and early stage fibrosis. In addition, HFHC diet 16 weeks but not 8 weeks is accompanied with weight gain and insulin resistance. The aim of this study ...
ORGANISM(S): Mus musculus 
2021-12-08 | GSE154426 | GEO
GenomicsChanges of hepatic gene expression in C57BL/6N male mice fed high-fat high-calorie fructose (HFHC) diet for 8 weeks
Changes of hepatic gene expression in C57BL/6N male mice fed high-fat high-calorie fructose (HFHC) diet for 8 weeks
PRJNA646237 | ENA
TranscriptomicsEffects of NAFLD/NASH on hepatic gene expression.
To characterize gene expression changes in arachidonic acid metabolism pathway genes in the presense of non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) mice administered were administered an atherogenic diet for a period of four weeks. Administration of the atherogenic...
ORGANISM(S): Mus musculus 
2014-01-03 | E-GEOD-53381 | biostudies-arrayexpress
Genomics
Liver tissue of HFHC-vehicle and HFHC-Gas mice induced by HFHC diet along with vehicle or Gas gavage
PRJNA756626 | ENA
TranscriptomicsHFHC induced MASLD mouse model
Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the leading causes for end-stage liver diseases with no effective pharmacological treatment. In this experiment, a high-fat high-cholesterol (HFHC) diet was used to construct a mouse MASLD model. After 16 weeks of MASLD diets...
ORGANISM(S): Mus musculus 
2026-10-07 | GSE297883 | GEO
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