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ProteomicsTargeting GSK3β's S/T-P Kinase Activity with an Interface-Specific Nanobody Reduces Ischemic Stroke Injury via Ferritin Nanoparticle Delivery
Proline-directed (S/T-P) phosphorylation constitutes a fundamental yet incompletely understood neural signaling mechanism implicated in cerebral pathophysiology, including ischemic stroke. Building on our prior identification of a regulatory domain controlling the proline-directed kinase activity of...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD067942 | Pride
Nanobody Gsk3β Neuroprotection Hfn nanoparticle Ischemia stroke Proline-directed phosphorylation 
TranscriptomicsTfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer
H-ferritin (HFn) nanocarrier is emerging as a promising theranostic platform for tumor diagnosis and therapy, which can specifically target tumor cells via binding transferrin receptor 1 (TfR1). This led us to investigate the therapeutic function of TfR1 in GC. The clinical significance ofTfR1 was a...
ORGANISM(S): Homo sapiens 
2023-01-01 | GSE143497 | GEO
UnknownThermostable iron oxide nanoparticle synthesis within recombinant ferritins from the hyperthermophile Pyrococcus yayanosii CH1.
Not available
S-EPMC9076106 | biostudies-literature
UnknownTfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer.
Not available
S-EPMC7002446 | biostudies-literature
UnknownIntegrin α2β1-targeting ferritin nanocarrier traverses the blood-brain barrier for effective glioma chemotherapy.
Not available
S-EPMC8201891 | biostudies-literature
UnknownH-ferritin-nanocaged gadolinium nanoparticles for ultra-sensitive MR molecular imaging.
Not available
S-EPMC10945347 | biostudies-literature
GenomicsTfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer
TfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer
PRJNA600833 | ENA
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