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MetabolomicsUntargeted Metabolomic Profiling of Left Ventricular Myocardium in a Mouse Model of Diabetic Cardiomyopathy
This study characterizes metabolic alterations in the left ventricular myocardium of a high-fat diet and streptozotocin-induced mouse model of diabetic cardiomyopathy. Untargeted LC–MS/MS metabolomics was performed using a Vanquish UHPLC system coupled to an Orbitrap Exploris 120 mass spectrometer. ...
2026-07-20 | MTBLS15043 | MetaboLights
MetabolomicsUltraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model
This study aims to identify biomarkers for evaluating the therapeutic efficacy of mesalazine on ulcerative colitis by metabolomics and lipidomics. A dextran sulfate sodium-induced mouse model was used. The disease status was assessed by a disease activity index, the TNF-α level of colon was measured...
2022-10-24 | MTBLS2111 | MetaboLights
UnknownCRISPhieRmix: a hierarchical mixture model for CRISPR pooled screens.
Not available
S-EPMC6176515 | biostudies-literature
UnknownEstimating mono- and bi-phasic regression parameters using a mixture piecewise linear Bayesian hierarchical model.
Not available
S-EPMC5516991 | biostudies-literature
UnknownA Hierarchical Bayesian Mixture Model Approach for Analysis of Resting-State Functional Brain Connectivity: An Alternative to Thresholding.
Not available
S-EPMC7310299 | biostudies-literature
TranscriptomicsGenome-wide characterization of light-inducible responses reveals a hierarchical light-sensing cascade in N. crassa
To better understand the roles of WC-1, WC-2 and other putative photoreceptors in mediation of light signals and to identify new components in light sensing cascades, we used microarrays with genome-wide coverage to characterize light-inducible transcriptional changes in Neurospora crassa. After uns...
ORGANISM(S): Neurospora crassa 
2009-03-08 | E-GEOD-8932 | biostudies-arrayexpress
UnknownHCMMCNVs: Hierarchical Clustering Mixture Model of Copy Number Variants Detection using Whole Exome Sequencing Technology.
Not available
S-EPMC8479678 | biostudies-literature
UnknownA hierarchical Bayesian mixture model for inferring the expression state of genes in transcriptomes.
Not available
S-EPMC7431084 | biostudies-literature
UnknownA model-based clustering via mixture of hierarchical models with covariate adjustment for detecting differentially expressed genes from paired design.
Not available
S-EPMC10633962 | biostudies-literature
UnknownCompound hierarchical correlated beta mixture with an application to cluster mouse transcription factor DNA binding data.
Not available
S-EPMC4701176 | biostudies-literature
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