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MetabolomicsComparison of singlequad and Orbitrap mass analyzer coupled to gas chromatography reveals potential of high resolution GC MS for untargeted metabolomics

The development of improved spectrometers and supporting computational tools is expected to eventually enable the rapid annotation of whole metabolomes. However, rarely are novel mass spectrometers directly compared to the previously used ones in the field of metabolomics, thus preventing researc...

2020-01-24 | MTBLS1104 | MetaboLights
ProteomicsThe Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, High Performance Quadrupole and an Ultra-High Field Orbitrap Analyzer
The quadrupole Orbitrap mass spectrometer (Q Exactive) has made a powerful proteomics instrument available in a benchtop format. It significantly boosted analyzable proteins per hour and has now evolved into a proteomics analysis workhorse for many laboratories. Here we describe the Q Exactive Plus ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080865 | MassIVE
ProteomicsThe Q Exactive HF, a Benchtop Mass Spectrometer with a Pre-filter, High Performance Quadrupole and an Ultra-High Field Orbitrap Analyzer
The quadrupole Orbitrap mass spectrometer (Q Exactive) has made a powerful proteomics instrument available in a benchtop format. It significantly boosted analyzable proteins per hour and has now evolved into a proteomics analysis workhorse for many laboratories. Here we describe the Q Exactive Plus ...
ORGANISM(S): Homo sapiens (Human) 
2014-11-10 | PXD001203 | Pride
Segmented quadrupole Q exactive hf Orbitrap ultra-high field Q exactive plus Quadrupole pre-filter Shotgun proteomics 
OtherRapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer.
Data from ProteomeXchange, PXD ID: PXD001305. Experiment: UPLC9_RJC_DEV_HeLa_03, file: 20140418_QE7_UPLC9_RJC_DEV_HeLaFrac10_03.mzml. Published as part of J Proteome Res. 2014 Oct 28 . From the Abstract: {{i}} Here, we investigate faster sequencing speed of the latest Q Exactive HF mass spectromete...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM11210030961 | GPMDB
Resource Reanalysis 
OtherRapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer.
Data from ProteomeXchange, PXD ID: PXD001305. Experiment: UPLC9_RJC_DEV_HeLa_02, file: 20140418_QE7_UPLC9_RJC_DEV_HeLaFrac1_02.mzml. Published as part of J Proteome Res. 2014 Oct 28 . From the Abstract: {{i}} Here, we investigate faster sequencing speed of the latest Q Exactive HF mass spectrometer...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320004807 | GPMDB
Resource Reanalysis 
ProteomicsUltra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes
Although only a few years old, the combination of a linear ion trap with an Orbitrap analyzer has become one of the standard mass spectrometers to characterize proteins and proteomes. Here we describe a novel version of this instrument family, the Orbitrap Elite, which is improved in three main area...
ORGANISM(S): Homo sapiens (Human) 
2013-10-10 | PXD000508 | Pride
Cid High-field orbitrap analyzer Hcd Top down Shotgun proteomics 
ProteomicsRapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
The faster sequencing speed available on the latest Q Exactive HF mass spectrometer is investigated and evaluated by four different acquisition methods and benchmarked across three generations of Q Exactive instruments. Also the instrument capabilities for offline high pH reversed-phase peptide frac...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-01 | MSV000079548 | MassIVE
UnknownThe Q Exactive HF, a Benchtop mass spectrometer with a pre-filter, high-performance quadrupole and an ultra-high-field Orbitrap analyzer.
Not available
S-EPMC4256516 | biostudies-literature
UnknownTop-down analysis of immunoglobulin G isotypes 1 and 2 with electron transfer dissociation on a high-field Orbitrap mass spectrometer.
Not available
S-EPMC5478168 | biostudies-literature
UnknownEvaluation of the compact high-field orbitrap for top-down proteomics of human cells.
Not available
S-EPMC3437942 | biostudies-literature
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