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Over 170 post-transcriptional RNA modifications have been described and are common in all kingdoms of life. These modifications range from methylation to complex chemical structures, with methylation being the most abundant. RNA modifications play a key role in RNA folding and function and their ...

2023-10-26 | MTBLS2959 | MetaboLights

Over 170 post-transcriptional RNA modifications have been described and are common in all kingdoms of life. These modifications range from methylation to complex chemical structures, with methylation being the most abundant. RNA modifications play a key role in RNA folding and function and their ...

2023-10-26 | MTBLS2497 | MetaboLights
The major objective of our study was to find out what are the extra costs and what optimization and adjustment steps of a high-flow LC-MS system have to be undertaken to identify a comparable number of proteins as on a nanoLC-MS system.
ORGANISM(S): Homo sapiens (Human) 
2019-11-07 | PXD005481 | Pride
The Antarctic green alga Chlamydomonas sp. UWO241 (UWO241) survives in the deep photoc zone of the permanently ice-covered Lake Bonney in the McMurdo Dry Valleys. The extreme habitat in its natural environment has given way to unique adaptive mechanisms in this halotolerant psychrophile. One of the ...
ORGANISM(S): Chlamydomonas Sp. Uwo 241 
Great advances have been made to quantify proteomes at depth and high precision. However, the inherent complexity of the proteome still creates huge challenges to deal with large sample series and longitudinal experiments. Here we report a data-independent acquisition (DIA) method, Scanning SWATH, a...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2021-03-02 | PXD023613 | Pride
The Antarctic green alga Chlamydomonas sp. UWO241 (UWO241) survives in the deep photoc zone of the permanently ice-covered Lake Bonney in the McMurdo Dry Valleys. The extreme habitat in its natural environment has given way to unique adaptive mechanisms in this halotolerant psychrophile. One of the ...
ORGANISM(S): Chlamydomonas Sp. Uwo 241 
The aim of the study was to address the concept of field cancerization in oral cancer. The presence of genomic aberrations, indicative of chromosomal instability (CIN), in oral distant fields (ODFs) of visually normal and non-dysplastic mucosa at the mirror image from concomitant oral potentially ma...
ORGANISM(S): Homo sapiens 
Atherosclerosis is causally related to disturbed flow through low and oscillatory shear stress. In order to study the miR expression profile in atherosclerotic plaques induced by disturbed flow, partial ligation of the carotid artery was performed. This procedure results acutely in severly reduced b...
ORGANISM(S): Mus musculus 
Rapid high-resolution detection of colistin resistance in Gram-negative bacteria using flow cytometry: a comparison with broth microdilution, a commercial screening test and whole genome sequencing
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