Sort   by:  
 Page size 
ProteomicsThunder-DDA-PASEF enables high-coverage immunopeptidomics and is boosted by MS2Rescore with novel MS2PIP timsTOF fragmentation prediction model
Human leukocyte antigen (HLA) class I peptide ligands (HLAIps) are key targets for developing vaccines and immunotherapies against infectious pathogens or cancer cells. Identifying HLAIps is challenging due to their high diversity, low abundance, and patient individuality. Here, we developed a highl...
ORGANISM(S): Homo Sapiens (human) 
2024-03-18 | PXD040385 | JPOST Repository
ProteomicsChromatomes of GR and SUMO2/3 identified with RIME
We identified GR and SUMO2/3 chromatomes in B-cell acute leukemia cells (NALM6) and studied the impact of SUMOylation inhibition (SUMOi) on them utilizing small molecule inhibitor ML792. Chromatome members were identified with Rapid Immunoprecipitation Mass spectrometry of Endogenous proteins (RIME)...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051304 | Pride
Human Cancer Immunoprecipitation Mass spectrometry Chromatin 
ProteomicsA deep-learning framework reveals whole-body perturbations at cell level
Many diseases, including obesity, have systemic effects that perturb multiple organ systems throughout the body. However, tools for comprehensive, high-resolution analysis of disease-associated changes at the whole-body scale have been lacking. Here we developed MouseMapper, a suite of foundation-mo...
ORGANISM(S): Homo sapiens (Human) 
2026-05-06 | PXD071172 | Pride
Human Brain Bruker Mouse Timstofscp Obesity Ganglion 
ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Secreted proteins
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-20 | PXD035987 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Cytoplasmic proteins
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-20 | PXD036017 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsMesothelioma-associated fibroblasts enhance proliferation and migration of malignant pleural mesothelioma cells via Met/PI3K and WNT signaling but do not protect against cisplatin_Proteins from nuclear extracts
Introduction: Malignant pleural mesothelioma (MPM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, MPM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving oncogene mutations indicates an extrinsic supp...
ORGANISM(S): Homo sapiens (Human) 
2023-06-19 | PXD036127 | Pride
Human malignant pleural mesothelioma-associated fibroblasts (cafs) High-resolution timstof-based proteomics analyses Cisplatin 
ProteomicsSpatial Proteomics Profiling of Vascular Smooth Muscle Cells and Atherosclerotic Plaques in a Diabetic Atherosclerosis Mouse Model
This project presents a spatial proteomic investigation of vascular smooth muscle cells (VSMCs) and atherosclerotic plaque regions in a diabetic mouse model of atherosclerosis (DMAS). Using ApoE-/- mice fed with a high-fat diet and treated with low-dose streptozotocin (STZ) to induce a diabetic phen...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD063231 | Pride
Diabetes mellitus  atherosclerosis  spatial proteomic technology 
ProteomicsProtein phosphorylation networks in Baylisascaris procyonis revealed by phosphoproteomic analysis
Background: Baylisascaris procyonis is an intestinal ascarid worm that parasitizes in raccoons and causes fatal neural, visceral, and ocular larva migrans in humans. Phosphorylated proteins and protein kinases have been studied as vaccine and drug target candidates against parasitic infections. Howe...
ORGANISM(S): Baylisascaris procyonis 
2025-08-04 | PXD066529 | Pride
Raccoon Liquid chromatography-mass spectrometry Signaling pathway Baylisascaris procyonis Phosphoproteome Function 
Sort   by:  
 Page size