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TranscriptomicsA distinct microRNA signature for definitive endoderm derived from human embryonic stem cells
This SuperSeries is composed of the following subset Series: GSE16678: MicroRNA expression data from differentiation of human Cyt49 ESCs into definitive endoderm in feeder-free conditions GSE16681: mRNA expression data from differentiation of human ESCs into definitive endoderm, Cyt49 on matrigel GS...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-16690 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression data from differentiation of human Cyt49 ESCs into definitive endoderm in feeder-free conditions
Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung). We used microarrays to detail the changes ...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-16678 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression data from differentiation of human Cyt49 ESCs into definitive endoderm on MEF feeder layers
Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung) We used microarrays to detail the changes i...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-16687 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression data from differentiation of human H9 ESCs into definitive endoderm on MEF feeder layers
Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm (DE) is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung). We used microarrays to detail the cha...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-16689 | biostudies-arrayexpress
TranscriptomicsmRNA expression data from differentiation of human ESCs into definitive endoderm, Cyt49 on matrigel
hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm (DE) is the first step into the pathway to endoderm derived tissues: pancreas, liver, gut, lung. We used microarrays to detail the changes in mRNA e...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-16681 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of E. coli NCTC 9001 challenged with four different cationic antimicrobial peptides
Obtaining an in depth understanding of the arms races between peptides comprising the innate immune response and bacterial pathogens is of fundamental interest and will inform the development of new antibacterial therapeutics. Many cationic antimicrobial peptides (AMPs) share a range of structural a...
ORGANISM(S): Escherichia coli 
2014-01-21 | E-MTAB-1703 | biostudies-arrayexpress
TranscriptomicsProfiling of miR-148a responsive genes in HeLa cells
Comparision of HeLa cells transfected with miR-148a mimic or scramble control for 48h
ORGANISM(S): Homo sapiens 
2015-01-13 | E-MTAB-2411 | biostudies-arrayexpress
TranscriptomicsIdentification of Sfh and H-NS binding sites in the Salmonella Typhimurium genome
The global regulator H-NS represses transcription in gram negative bacteria. Sfh is a homologue of H-NS and is encoded by plasmid pSfR27. Sfh provides a 'stealth' function that allows pSfR27 to be transmitted to a new host without disrupting the competitive fitness of the new host We used ChIP-on-ch...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2010-05-18 | E-GEOD-19231 | biostudies-arrayexpress
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
TranscriptomicsAnchoring ethinylestradiol induced gene expression changes with testicular morphology and reproductive function in the medaka
This study assessed the implications of a 14 day sub-chronic exposure of ethinylestradiol (EE2; 1.0 or 10.0 M-BM-5g/L EE2) on male medaka fertility, testicular histology and testicular gene expression. The findings demonstrate that a 14 day exposure to EE2 induced impaired male reproductive capacity...
ORGANISM(S): Oryzias latipes 
2013-03-06 | E-GEOD-44859 | biostudies-arrayexpress
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