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Metabolomics1H NMR Urinary Metabolomic Analysis in Older Adults after Hip Fracture Surgery May Provide Valuable Information for Patient Profiling-A Preliminary Investigation
In these times of precision and personalized medicine, profiling patients to identify their needs is crucial to providing the best and most cost-effective treatment. In this study, we used urine metabolomics to explore the characterization of older adults with hip fractures and to explore the foreca...
2022-10-31 | MTBLS2903 | MetaboLights
TranscriptomicsRegulation of transcription by HIPPI and its molecular partner HIP1
This SuperSeries is composed of the following subset Series: GSE26115: Regulation of transcription by HIP1 protein interactor (HIPPI) in HeLa cells GSE26116: Role of HIP1 in HIPPI mediated transcription regulation in HeLa cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-09-20 | E-GEOD-26117 | biostudies-arrayexpress
ProteomicsTargeted inhibition of NRF2 reduces the invasive and metastatic ability of HIP1 depleted lung cancer cells.
Background: Non-Small Cell Lung Cancer (NSCLC) presents as a highly metastatic disease with Kras and P53 as prevalent oncogenic driver mutations. Endocytosis, through its role in receptor recycling and enrichment, is important for cancer cell proliferation and metastasis. Huntingtin Interacting Prot...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD054307 | Pride
Nsclc Hip1 Nrf2 
TranscriptomicsRole of HIP1 in HIPPI mediated transcription regulation in HeLa cells
Nuclear entry of transcription factor HIPPI is mediated by its interacting partner Huntingtin Interacting Protein 1 (HIP1), a nuclear localization signal containing nucleo-cytoplasmic shuttling protein. In oredr to investigate the role of HIP1 in HIPPI mediated transcriptional regulation in cell, he...
ORGANISM(S): Homo sapiens 
2011-09-20 | E-GEOD-26116 | biostudies-arrayexpress
ProteomicsMass Spectometry of rat synovial fibroblasts immunoprecipitated with anti-HIP1
Identify HIP1 binding proteins implicated in regulation of invasive property of Rheumatoid Arthritis (RA) fibroblast-like synoviocytes (FLS) by using FLS cell line from arthritic DA (highly invasive) and R6 (minimally invasive) arthritis-protected congenic rats, which differ in amino-acid changing ...
ORGANISM(S): Rattus rattus (Black rat) 
2024-04-18 | PXD051384 | Pride
Fls Hip1 Arthritis 
TranscriptomicsHIP1 mediates prostate carcinogenesis and progression through STAT3 signalling
Overexpression of HIP1 has been associated with fibroblast transformation, increasing grades of prostate cancer (CaP), and biochemical relapse. Here we demonstrate cellular transformation and phenotypic effects of HIP1 overexpression in a benign prostate epithelial cell line to be dependent on STAT3...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-35211 | biostudies-arrayexpress
TranscriptomicsHIP1 mediates prostate carcinogenesis and progression through STAT3 signalling
Overexpression of HIP1 has been associated with fibroblast transformation, increasing grades of prostate cancer (CaP), and biochemical relapse. Here we demonstrate cellular transformation and phenotypic effects of HIP1 overexpression in a benign prostate epithelial cell line to be dependent on STAT3...
ORGANISM(S): Homo sapiens 
2016-09-01 | GSE35211 | GEO
TranscriptomicsRole of HIP1 in HIPPI mediated transcription regulation in HeLa cells
Nuclear entry of transcription factor HIPPI is mediated by its interacting partner Huntingtin Interacting Protein 1 (HIP1), a nuclear localization signal containing nucleo-cytoplasmic shuttling protein. In oredr to investigate the role of HIP1 in HIPPI mediated transcriptional regulation in cell, he...
ORGANISM(S): Homo sapiens 
2011-09-21 | GSE26116 | GEO
UnknownHip1-related mutant mice grow and develop normally but have accelerated spinal abnormalities and dwarfism in the absence of HIP1.
Not available
S-EPMC400480 | biostudies-literature
UnknownActin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain.
Not available
S-EPMC2583295 | biostudies-literature
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