Sort   by:  
 Page size 
TranscriptomicsExpression data (U133 Plus 2.0) from fibroblast like synoviocytes from patients with rheumatoid arthritis (RA-FLS) stimulated by DcR3
Decoy receptor 3 (DcR3), a member of the tumor necrosis factor receptor (TNFR) superfamily, competitively binds and inhibits members of the TNF family, including Fas ligand (FasL), LIGHT, and TL1A. DcR3 was recently reported not only to act as a decoy receptor for these TNFRs but also to play a role...
ORGANISM(S): Homo sapiens 
2013-04-02 | E-GEOD-45665 | biostudies-arrayexpress
TranscriptomicsExpression data (U133 Plus 2.0) from fibroblast like synoviocytes from patients with rheumatoid arthritis (RA-FLS) stimulated by TL1A
TNF-like ligand 1A (TL1A) is a member of TNF receptor superfamily and involved in the pathogenesis of autoimmune diseases by inducing apoptosis via intracellular death domain or promoting inflammation through the activation of NFM-NM-:B by binding to its specific receptor death receptor 3 (DR3). Mea...
ORGANISM(S): Homo sapiens 
2014-12-10 | E-GEOD-63995 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiles of synoviocytes and macrophages in patients with rheumatoid arthritis and osteoarthritis
Rheumatoid synoviocytes, which consist of fibroblast-like synoviocytes (FLS) and synovial macrophages (SM), are crucial for the progression of rheumatoid arthritis (RA). Particularly, FLS of RA patients (RA-FLS) exhibit invasive characteristics reminiscent of cancer cells, destroying cartilage and b...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-49604 | biostudies-arrayexpress
TranscriptomicsDifferential effects of TNFalpha and IL1beta on FLS global gene expression profile
TNFalpha and IL1beta play a pathogenic role in rheumatoid arthritis. Both cytokines are known to activate cytokine and metalloproteinase secretion by synovial fibroblasts. In the present study, we wanted to investigate whether TNFalpha and IL1beta displayed differential effects on cultured Fibroblas...
ORGANISM(S): Homo sapiens 
2009-04-15 | E-GEOD-15615 | biostudies-arrayexpress
TranscriptomicsThe FLS (Fatty liver Shionogi) mouse, liver with non-alcoholic steatohepatitis (NASH)
Comparison between livers of FLS mice and livers of DS (DD shionogi) mice We used FLS mice as model animals of human NASH, while DS mice as control animals. FLS mice develops NASH spontaneously. DS mouse strain is a sister strain of the FLS mouse strain. We compared RNA from pooled livers of three F...
ORGANISM(S): Mus musculus 
2013-03-30 | E-GEOD-45624 | biostudies-arrayexpress
GenomicsExpression data from Fibroblast-like Synoviocytes (FLS) isolated from patients with Juvenile Idiopathic Arthritis (JIA) - compares untreated FLS to FLS exposed to conditioned media from Chondrocytes (Ch)
Expression data from Fibroblast-like Synoviocytes (FLS) isolated from patients with Juvenile Idiopathic Arthritis (JIA) - compares untreated FLS to FLS exposed to conditioned media from Chondrocytes (Ch)
PRJNA695234 | ENA
ProteomicsMass Spectometry of rat synovial fibroblasts immunoprecipitated with anti-HIP1
Identify HIP1 binding proteins implicated in regulation of invasive property of Rheumatoid Arthritis (RA) fibroblast-like synoviocytes (FLS) by using FLS cell line from arthritic DA (highly invasive) and R6 (minimally invasive) arthritis-protected congenic rats, which differ in amino-acid changing ...
ORGANISM(S): Rattus rattus (Black rat) 
2024-04-18 | PXD051384 | Pride
Fls Hip1 Arthritis 
TranscriptomicsDNA methylome signature in rheumatoid arthritis
Objectives: Epigenetics can influence disease susceptibility and severity. While DNA methylation of individual genes has been explored in autoimmunity, no unbiased systematic analyses have been reported. Therefore, a genome-wide evaluation of DNA methylation loci in fibroblast-like synoviocytes (FLS...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-46364 | biostudies-arrayexpress
GenomicsComprehensive Epigenetic Landscape of Rheumatoid Arthritis FLS
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis FLS
PRJNA474568 | ENA
GenomicsComprehensive Epigenetic Landscape of Rheumatoid Arthritis FLS
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis FLS
PRJNA474569 | ENA
Sort   by:  
 Page size