Sort   by:  
 Page size 
TranscriptomicsdKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing.
Transcription regulation involves enzyme-mediated changes in chromatin structure. Here, we describe a novel mode of histone crosstalk during gene silencing, in which histone H2A monoubiquitylation is coupled to the removal of histone H3 Lys 36 dimethylation (H3K36me2). This pathway was uncovered thr...
ORGANISM(S): Drosophila melanogaster 
2011-12-13 | E-GEOD-34390 | biostudies-arrayexpress
TranscriptomicsHistone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat
In Saccharomyces cerevisiae, ubiquitylation of histone H2B signals methylation of histone H3 at lysine residues 4 (K4) and 79. These modifications occur at active genes but are believed to stabilize silent chromatin by limiting movement of silencing proteins away from heterochromatin domains. In the...
ORGANISM(S): Saccharomyces cerevisiae 
2011-12-02 | E-GEOD-27934 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Microarray Analysis of Histone H2B Ubiquitylation mutant strains of Tetrahymena thermophila
Microarray analyses were performed to compare the gene expression profiles of wild-type and several mutant strains of the ciliated protozoan Tetrahymena thermophila. Elimination of H3K4 methylation (hht2-K4Q) and knockout of either of the ubiquitylation enzymes (delta-UBC2 and delta-BRE1) affects a ...
ORGANISM(S): Tetrahymena thermophila 
2010-06-20 | E-GEOD-18743 | biostudies-arrayexpress
ProteomicsTwo DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids
In higher eukaryotes, a single DOT1 histone H3 lysine 79 (H3K79) methyltransferase processively produces H3K79me2/me3 from me0 through histone H2B mono-ubiquitin interaction. The early-branched kinetoplastid Trypanosoma brucei harbors the essential H3K76 di-methyltransferase DOT1A and the non-essent...
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2022-11-09 | MSV000090680 | MassIVE
ProteomicsHemi-methylated DNA regulates DNA methylation inheritance through allosteric control of H3 ubiquitylation by UHRF1
DNA methylation is a heritable chromatin modification essential to mammalian development that functions with histone post-translational modifications to regulate chromatin structure and gene expression programs. The epigenetic inheritance of DNA methylation requires the combined actions of DNMT1 and...
ORGANISM(S): Homo sapiens (Human) 
2016-08-25 | PXD003983 | Pride
Uhrf1 Ring e3 ligase Epigenetics Histone post-translational modifications Dna methylation Ubiquitin Histone h3 ubiquitylation 
TranscriptomicsGenome-wide analysis of histone H3.1 and H3.3 variants in Arabidopsis thaliana
Nucleosomes package eukaryotic DNA and are composed of four different histone proteins, H3, H4, H2A and H2B. Histone H3 has two main variants, H3.1 and H3.3, which show different genomic localization patterns in animals. We profiled H3.1 and H3.3 variants in the genome of the plant Arabidopsis thali...
ORGANISM(S): Arabidopsis thaliana 
2012-03-05 | E-GEOD-34840 | biostudies-arrayexpress
GenomicsStress controls heterochromatin inheritance through histone H3 ubiquitylation [ChIP-Seq]
Stress controls heterochromatin inheritance through histone H3 ubiquitylation [ChIP-Seq]
PRJNA1179880 | ENA
GenomicsStress controls heterochromatin inheritance through histone H3 ubiquitylation [RNA-Seq]
Stress controls heterochromatin inheritance through histone H3 ubiquitylation [RNA-Seq]
PRJNA1179478 | ENA
UnknownHistone H2B ubiquitylation is not required for histone H3 methylation at lysine 4 in tetrahymena.
Not available
S-EPMC2787349 | biostudies-literature
UnknownRAG1-mediated ubiquitylation of histone H3 is required for chromosomal V(D)J recombination.
Not available
S-EPMC4650572 | biostudies-literature
Sort   by:  
 Page size