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OtherAKT1 AND AKT2 INDUCE DISTINCT PHOSPHORYLATION PATTERNS IN HL-1 CARDIAC MYOCYTES.
Data from ProteomeXchange, PXD ID: PXD000268. Experiment: DML2, file: folder summary. Published as part of J Proteome Res. 2014 Aug 27 . From the Abstract: {{i}} ... To gain more insight into AKT isoform specific signaling at the molecular level we investigated the phosphoproteome of HL-1 cardiomyo...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32310003337 | GPMDB
Resource Reanalysis 
UnknownTWEAK/Fn14 mediates atrial-derived HL-1 myocytes hypertrophy via JAK2/STAT3 signalling pathway.
Not available
S-EPMC6111870 | biostudies-literature
ProteomicsAKT isoform specific signaling
Phosphoproteome analysis of HL-1 cardiomyocytes carrying AKT1 or AKT2 isoform specific knock down, respectively. Six biological replicates were analysed. Cells were grown until reaching 90 % confluency, starved for 50 minutes followed by stimulation with 200 nM insulin for 10 minutes. In solution st...
ORGANISM(S): Mus musculus (Mouse) 
2014-08-28 | PXD000268 | Pride
Ltq-orbitrap Phosphoproteome Akt Hl-1 cardiac myocytes 
TranscriptomicsRNA-seq of Immortalized cardiac cell lines for characterization and comparison
The aim of this study was to compare the most common immortalized cardiac cell lines (human: AC16, rat: H9C2, mouse: HL-1) to primary cultures (neonatal rat or mouse cardiomyocytes, and human induced pluripotent stem cells) and left ventricular tissues from the corresponding species. To characterize...
ORGANISM(S): Homo sapiens 
2021-10-06 | E-MTAB-10720 | biostudies-arrayexpress
TranscriptomicsImmortalized cardiac cell line characterization and comparison (mouse/mouse-derived)
The aim of this study was to compare the most common immortalized cardiac cell lines (human: AC16, rat: H9C2, mouse: HL-1) to primary cultures (neonatal rat or mouse cardiomyocytes, and human induced pluripotent stem cells) and left ventricular tissues from the corresponding species. To characterize...
ORGANISM(S): Mus musculus 
2022-01-04 | E-MTAB-10912 | biostudies-arrayexpress
TranscriptomicsImmortalized cardiac cell line characterization and comparison (rat/rat-derived)
The aim of this study was to compare the most common immortalized cardiac cell lines (human: AC16, rat: H9C2, mouse: HL-1) to primary cultures (neonatal rat or mouse cardiomyocytes, and human induced pluripotent stem cells) and left ventricular tissues from the corresponding species. To characterize...
ORGANISM(S): Rattus norvegicus 
2022-01-04 | E-MTAB-10913 | biostudies-arrayexpress
UnknownER stress modulates Kv1.5 channels via PERK branch in HL-1 atrial myocytes: Relevance to atrial arrhythmogenesis and the effect of tetramethylpyrazine.
Not available
S-EPMC11420496 | biostudies-literature
TranscriptomicsComplexity of Murine Cardiomyocyte miRNA Biogenesis, Sequence Variant Expression and Function
microRNAs (miRNAs) are critical to heart development and disease. Emerging research indicates that regulated precursor processing can give rise to an unexpected diversity of miRNA variants. We subjected small RNA from murine HL-1 cardiomyocyte cells to next generation sequencing to investigate the r...
ORGANISM(S): Mus musculus 
2012-07-20 | E-GEOD-39531 | biostudies-arrayexpress
TranscriptomicsSmall RNA sequencing in mouse cardiomyocytes after siRNA mediated knockdown of Srf
We performed two independent siRNA mediated knockdowns of Srf (Srf si1 & Srf si2) and an unspecific siRNA (siNon) in mouse cardiomyocytes HL-1 cells. Small RNAs were sequenced by Illumina/Solexa next-generation (single-end) sequencing technology. The sequence reads were mapped to the mouse reference...
ORGANISM(S): Mus musculus 
2011-01-03 | E-GEOD-19066 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse rapidly stimulated atrial myocytes: Conservation with human atrial fibrillation
Atrial fibrillation (AF) is a progressive arrhythmia for which current therapy is inadequate. During AF, rapid stimulation causes atrial remodeling that promotes further AF. The cellular signals that trigger this process remain poorly understood, however, and elucidation of these factors would likel...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-10598 | biostudies-arrayexpress
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