Sort   by:  
 Page size 
ProteomicsFrom incision to excision: active DNA damage eviction by HLTF stimulates repair
Nucleotide excision repair (NER) counteracts the onset of cancer and aging by removing helix-distorting DNA lesions via a ‘cut-and-patch’-type reaction. The regulatory mechanisms that drive NER through its successive damage recognition, verification, incision and gap restoration reaction steps remai...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD031243 | Pride
Uv damage response Hltf Repair synthesis Damage eviction Dna damage Tfiih Genome stability Post-replication repair Nucleotide excision repair 
GenomicsHLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
PRJNA1041318 | ENA
UnknownHLTF gene silencing in human colon cancer.
Not available
S-EPMC123687 | biostudies-literature
UnknownLoss of HLTF function promotes intestinal carcinogenesis.
Not available
S-EPMC3337324 | biostudies-literature
GenomicsHLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
G-quadruplexes (G4s) form throughout the genome and influence important cellular processes, but their deregulation can challenge DNA replication fork progression and threaten genome stability. Here, we demonstrate an unexpected, dual role for the dsDNA translocase HLTF in G4 metabolism. First, we fi...
ORGANISM(S): Homo sapiens 
2024-08-13 | GSE247967 | GEO
UnknownDTX2 promotes glioma development via regulation of HLTF.
Not available
S-EPMC10759338 | biostudies-literature
GenomicsAlternative splicing Hltf: intron retention-dependent activation of immune tolerance at the feto-maternal interface (Bisulfite-Seq)
Alternative splicing Hltf: intron retention-dependent activation of immune tolerance at the feto-maternal interface (Bisulfite-Seq)
PRJNA464408 | ENA
GenomicsAlternative splicing Hltf: intron retention-dependent activation of immune tolerance at the feto-maternal interface (RNA-Seq)
Alternative splicing Hltf: intron retention-dependent activation of immune tolerance at the feto-maternal interface (RNA-Seq)
PRJNA464407 | ENA
GenomicsHelicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice
PRJNA549162 | ENA
UnknownHuman HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination.
Not available
S-EPMC2268824 | biostudies-literature
Sort   by:  
 Page size