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ProteomicsProteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-deprived culture conditions
The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were trea...
ORGANISM(S): Homo sapiens (Human) 
2021-10-07 | PXD023163 | Pride
Hmc3 Cytokines Tumor Microglia 
ProteomicsProteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-enriched culture conditions
The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were trea...
ORGANISM(S): Homo sapiens (Human) 
2021-10-06 | PXD023166 | Pride
Hmc3 Cytokines Tumor Microglia 
GenomicsEffect of IL-33 in human microglia cell line (HMC3)
Effect of IL-33 in human microglia cell line (HMC3)
PRJNA1029962 | ENA
GenomicsNRF2 binding in HMC3 human microglia
NRF2 binding in HMC3 human microglia
PRJNA1281143 | ENA
ProteomicsBrucella suis S2 strain inhibits IRE1/Caspase-12/Caspase-3 pathway-mediated apoptosis of microglia HMC3 by affecting the ubiquitination of CALR
Neurobrucellosis is a serious complication of brucellosis, which poses a significant threat to human health and quality of life. The origin of this phenomenon is that the patients are more vulnerable to the development of chronic Brucella infection, which is also an important clinical problem. The r...
ORGANISM(S): Homo sapiens (Human) 
2025-02-20 | PXD056006 | Pride
Neurobrucellosis  brucella suis s2  endoplasmic reticulum stress  microglia  apoptosis 
TranscriptomicsEffect of IL-33 in human microglia cell line (HMC3)
To investigate the expression prolfile of genes regulated by IL-33 in HMC3.
ORGANISM(S): Homo sapiens 
2024-07-24 | GSE245785 | GEO
TranscriptomicsM1 microglia disrupt the barrier function of retinal microvascular endothelial cells via ANGPT2/TIE2 axis
Human microglial clone 3 cells (HMC3) was induced to M1 or M2 status, then co-cultured with retinal microvascular endothelial cells (hRMECs) in vitro.
ORGANISM(S): Homo sapiens 
2025-06-20 | E-MTAB-15209 | biostudies-arrayexpress
TranscriptomicsRNA-seq of control and TIA1-knockdown HMC3 cells
The study aims to utilize RNA-seq to characterize the transcriptomic alterations in TIA1-knockdown HMC3 cells compared to control cells, with the goal of identifying differentially expressed genes and elucidating the molecular pathways and biological processes regulated by TIA1, a key RNA-binding pr...
ORGANISM(S): Homo sapiens 
2025-05-24 | GSE297158 | GEO
GenomicsRNA-sequencing analysis of pro-inflammatory cytokine stimulation of HMC3 microglia and HOG oligodendroglioma cell lines
RNA-sequencing analysis of pro-inflammatory cytokine stimulation of HMC3 microglia and HOG oligodendroglioma cell lines
PRJNA824292 | ENA
ProteomicsGlobal Proteomic Analysis of Lysine lactylation in HMC3 cells under Normoxia or Hypoxia
This project carried out a quantitative study of lactylation in HMC3 Cell Line. In order to ensure a high degree of credibility of the results, we used the standard of localization probability>0.75 to filter the authentication data. In this study, a total of 3093 lactylation sites located on 1270 pr...
ORGANISM(S): Homo sapiens (Human) 
2023-03-28 | PXD028737 | Pride
Human 4d label-free platform Lactylation Hmc3 (cell line) 
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