Sort   by:  
 Page size 
TranscriptomicsGenome-wide analysis of serum starved prelamin A-accumulating hMSCs gene expression.
Analysis of serum starved prelamin A-accumulating hMSCs at gene expression level. The hypothesis tested in the present study was that prelamin A accumulation induces the dysregulation of genes that are essensial for cell survival under a stress condition such as serum starvation. The results provide...
ORGANISM(S): Homo sapiens 
2014-06-23 | E-GEOD-52563 | biostudies-arrayexpress
TranscriptomicseHSP70 promotes osteogenesis of hMSCs through activating ERK signaling pathway
Heat shock proteins are highly conserved proteins that, when produced intracellularly, protect stress exposed cells. It has been suggested that extracellular Hsp70 has both protective and deleterious effects. Our study showed eHSP70 increased the ALP activity, promoted mineralization and up-regulate...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-71080 | biostudies-arrayexpress
GenomicsChanges in gene expression of hMSCs and NOD/scid mouse lung after IV infusion of hMSCs
Changes in gene expression of hMSCs and NOD/scid mouse lung after IV infusion of hMSCs
PRJNA115547 | ENA
GenomicsStabilizing heterochromatin by ZKSCAN3 safeguards hMSCs from senescence
Stabilizing heterochromatin by ZKSCAN3 safeguards hMSCs from senescence
PRJNA611555 | ENA
TranscriptomicsPredicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1
Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To th...
ORGANISM(S): Homo sapiens 
2018-10-04 | E-MTAB-7210 | biostudies-arrayexpress
TranscriptomicsLactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependent manner
Wounds, especially non healing wounds are characterised by elevated tissue lactate concentrations. Lactate is known for being able to stimulate collagen synthesis and vessel growth. Lately it has been shown that lactate, in vivo, plays an important role in homing of stem cells. With this work we aim...
ORGANISM(S): Homo sapiens 
2013-01-09 | E-GEOD-40205 | biostudies-arrayexpress
TranscriptomicsPro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells
Human mesenchymal stromal cells (hMSCs) are able to differentiate into a wide variety of cell types, which makes them an interesting source for tissue engineering applications. On the other hand, these cells also secrete a broad panel of growth factors and cytokines that can exert trophic effects on...
ORGANISM(S): Homo sapiens 
2018-10-06 | E-MTAB-7224 | biostudies-arrayexpress
GenomicsATF4 Licenses C/EBPb Activity in Human Mesenchymal Stem Cells Primed for Adipogenesis
We report ChIP-seq for C/EBPb and ATF4 in human mesenchymal stem cells and in a cell-free system using naked genomic DNA. ChIP-Seq for GR, RNA Polymerase II, and H3K27 acetylation in hMSCs cultured under different adipogenic conditions are also presented. hMSCs cultured at high or low cell seeding d...
ORGANISM(S): Homo sapiens 
2015-06-25 | E-GEOD-68864 | biostudies-arrayexpress
TranscriptomicsHuman Mesenchymal Stem Cells (hMSCs): Fibroblast vs. hMSCs from various origins
To identify the key microRNAs (miRNAs) of hMSCs required for fate determination, miRNA profiling was performed with hMSCs from three different sources including adipose-derived stem cells (ADSCs), bone-marrow-derived stem cells (BMSCs), and umbilical cord-derived stem cells (UCSCs) versus fibroblast...
ORGANISM(S): Homo sapiens 
2014-05-05 | E-GEOD-57266 | biostudies-arrayexpress
ProteomicsProteomic profiling of human mesenchymal stem cells derived from umbilical cord or adipose tissue
We performed a proteomic profiling of human mesenchymal stem cells (hMSCs) derived from adipose tissue or umbilical cord.
ORGANISM(S): Homo sapiens (Human) 
2018-07-11 | PXD009893 | Pride
Adipose tissue Human mesenchymal stem cells Hmscs Umbilical cord 
Sort   by:  
 Page size