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MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
UnknownHierarchical organization of cortical and thalamic connectivity.
Not available
S-EPMC8433044 | biostudies-literature
UnknownRegional, Layer, and Cell-Type-Specific Connectivity of the Mouse Default Mode Network.
Not available
S-EPMC8150331 | biostudies-literature
UnknownClinical Deep Phenotyping of ABCA7 Mutation Carriers.
Not available
S-EPMC8759075 | biostudies-literature
UnknownTranscriptomic and spatial organization of telencephalic GABAergic neurons.
Not available
S-EPMC12589142 | biostudies-literature
TranscriptomicsTranscription profiling of human HLE B-3 cells transfected with hGSTA4-4 expressing vector vs. controls
HLE B-3 cells were transfected with either empty vector or hGSTA4-4 expressing vector to lower intracellular 4-hydroxynonenal levels. hGSTA4-transfected sample has lower HNE levels than pTarget-transfected sample.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2298 | biostudies-arrayexpress
UnknownMulti-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells.
Not available
S-EPMC12015978 | biostudies-literature
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownSecondary analysis of electronic opt-out consent in pragmatic research: A study design method to diversify clinical trials?
Not available
S-EPMC10286777 | biostudies-literature
Transcriptomics5-azacytidine and entinostat treatment of patients with MDS, chronic myelomonocytic leukemia (CMMoL), and high risk AML
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies. The patients with MDS, chronic myelomonocytic leukemia (CMMoL), and high risk AML were treated with sequential administration of ...
ORGANISM(S): Homo sapiens 
2009-06-20 | E-GEOD-16625 | biostudies-arrayexpress
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