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TranscriptomicsTranscription profiling of Drosophila samples of wild type, aly, can, zaa and zab testes
Drosophila melanogaster males mutant for any meiotic arrest gene have defective spermatogenesis, with cells arresting as primary spermatocytes, and failing to progress to later stages. This phenotype is remarkably similar to meiosis I maturation arrest azoospemia in humans. Drosophila meiotic arrest...
ORGANISM(S): Drosophila melanogaster 
2004-05-07 | E-FLYC-5 | biostudies-arrayexpress
MetabolomicsComparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth
Bacteria need nutrients from the host environment to survive, yet we know little about which biochemicals are present in the airways (the metabolome), which of these biochemicals are essential for bacterial growth and how they change with airway disease. The aims of this pilot study were to develop ...
2019-06-13 | MTBLS179 | MetaboLights
UnknownFamilial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer.
Not available
S-EPMC5522647 | biostudies-literature
UnknownSocial and Healthcare Disruptions Due to the COVID-19 Pandemic and Associations with Psychosocial Well-Being Among Cancer Survivors With and Without HIV: Findings from the MACS/WIHS Combined Cohort Study.
Not available
S-EPMC12908221 | biostudies-literature
Genomicsena-DATASET-THE UNIVERSITY OF HONG KONG DEPARTMENT OF PATHOLOGY AND PFIZER INC.-18-12-2019-11:12:21:554-1297 - samples
Four micrograms of total RNA was used for cDNA library construction using the KAPA Stranded mRNA-Seq Kit (KR0960-v3.15), following manufacturer's protocol. The adaptor-ligated libraries were enriched by 6 cycles of polymerase chain reaction (PCR). Libraries were sequenced using the Novaseq 6000 with...
EGAD00001005753 | EGA
Genomicsena-DATASET-THE UNIVERSITY OF HONG KONG DEPARTMENT OF PATHOLOGY AND PFIZER INC.-20-12-2019-08:50:56:915-1359 - samples
Five hundred nanograms of genomic DNA was fragmented by Covaris S2, the fragmented DNAs were performed end-repair, A-tailing at the 3 prime end, adaptors ligation with an IDT dual-indexed UMI adaptor system at the terminal ends. The adapter ligated library with size range 300-750bp were selected by...
EGAD00001005759 | EGA
Genomicsena-DATASET-THE UNIVERSITY OF HONG KONG DEPARTMENT OF PATHOLOGY AND PFIZER INC.-18-12-2019-11:18:36:686-1298 - samples
Five hundred fifty nanograms of genomic DNA were input for library preparation after fragmentation by Covaris S2, following the KAPA Hyper Prep Kit (KR0961-V1.14) protocols, with selection for a library size range of 250-450 bp. Three hundred nanograms per library DNA each from 12 samples were norma...
EGAD00001005754 | EGA
GenomicsOrganoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles
Sporadic early-onset colorectal cancer (EOCRC) has bad prognosis, yet is poorly represented by cell line models. We examine the key mutational and transcriptomic alterations in an organoid biobank enriched in EOCRCs. We established paired cancer (n=32) and normal organoids (n=18) from 20 patients en...
EGAS00001004063 | EGA
GenomicsThe University of Hong Kong Colon Cancer Organoids Genomics Study Data Access Committee
Data Access Committee EGAC00001001405
EGAC00001001405 | EGA
UnknownSociety for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer.
Not available
S-EPMC8365813 | biostudies-literature
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