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ProteomicsHBPP_MultipleSclerosis_Phos
HBPP_MultipleSclerosis_Phospho
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005154 | PeptideAtlas
ProteomicsHBPP_NormalControl_Phos
HBPP_NormalControl_Phospho
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005150 | PeptideAtlas
ProteomicsMice with FIA develop anti-native and anti-in vitro citrullinated fibrinogen antibodies
Synovial antigen arrays were probed with 1:150 dilutions of plasma derived from SJL mice immunized with fibrinogen emulsified in CFA or with CFA alone. Autoantibody binding was detected with a Cy3-conjugated goat-anti-mouse IgG/M secondary antibody. SAM was applied to identify antigens with statis...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18023 | biostudies-arrayexpress
ProteomicsFIA plasma induces arthritis in naïve mice
Plasma collected from mice with FIA were pooled, and 0.3 ml was injected intravenously into 6-week-old naïve SJL mice on days 0 and 2. Synovial antigen array profiling of plasma from the arthritic recipient mice demonstrated autoreactive B-cell responses against peptides representing native fibrino...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18024 | biostudies-arrayexpress
ProteomicsFibrinogen-reactive T cells transfer disease to naïve mice
Splenocytes harvested from mice with FIA were cultured in vitro and stimulated with 0.01 mg/ml fibrinogen for 3 days. Enriched T cells were transferred into 6-week-old naïve SJL mice, which developed visible signs of arthritis within 2 weeks. Synovial array profiling of plasma from the arthritic ...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-18025 | biostudies-arrayexpress
ProteomicsThe B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM
This data set contains the mass spectrometry raw files for the paper The B Cell Repertoire in Multiple Sclerosis Reveals Molecular Mimicry between EBNA1 and GlialCAM. In multiple sclerosis (MS) intrathecal B lymphocytes are directly involved in inflammation and secrete oligoclonal immunoglobulin. Ho...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-02-11 | MSV000086842 | MassIVE
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