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UnknownRandomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer.
Not available
S-EPMC6804854 | biostudies-literature
TranscriptomicsIdentifying multi-locus chromatin contacts in human cells using tethered multiple 3C
Background: DNA in the nucleus of a living cell carries out its functions in the context of a complex, three-dimensional chromatin architecture. Several recently developed methods, each an extension of the chromatin conformation capture (3C) assay, have enabled the genome-wide profiling of chroma...
ORGANISM(S): Homo sapiens 
2015-04-29 | E-GEOD-60623 | biostudies-arrayexpress
TranscriptomicsInvestigation of the mechansim underlying the inflammatory phenotype in Group A ependymoma
Inflammatory response has been identified as a molecular signature of high-risk Group A ependymoma (EPN). To better understand the biology of this phenotype and aid therapeutic development, transcriptomic data from Group A and B EPN patient tumor samples, and additional malignant and normal brain da...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-66354 | biostudies-arrayexpress
TranscriptomicsTranslation State Array Assay for C elegans IFE-1-dependent mRNAs
Relative polysomal loading changes for wild type (N2) versus ife-1(bn127) C. elegans strains Strain ife-1(bn127) is null for the gene encoding one of five eIF4E isoforms in the worm, IFE-1. Only this isoform associates with P granules. Resolution of translating and non-translating mRNAs from WT and...
ORGANISM(S): Caenorhabditis elegans 
2016-01-07 | E-GEOD-74459 | biostudies-arrayexpress
ProteomicsGlobal phosphoproteomic mapping of early mitotic exit in human cells identifies novel substrate dephosphorylation motifs
Entry into mitosis is driven by the coordinated phosphorylation of thousands of proteins. For the cell to complete mitosis and divide into two identical daughter cells it must regulate dephosphorylation of these proteins in a highly ordered, temporal manner. There is currently a lack of a complete u...
ORGANISM(S): Homo sapiens (Human) 
2015-06-25 | PXD001559 | Pride
Motif Spindle assembly checkpoint. Mitosis Phosphatase Silac Prc1 Myc Phosphorylation Mitotic exit Kinase Phosphoproteomics 
TranscriptomicsExpression data from human brain tumors and human normal brain
The characteristics of immune cells infiltrating pediatric brain tumors is largely unexplored. A better understanding of these characteristics will provide a foundation for development of immunotherapy for pediatric brain tumors. Gene expression profiles were used to identify immune marker gene that...
ORGANISM(S): Homo sapiens 
2013-08-25 | E-GEOD-50161 | biostudies-arrayexpress
ProteomicsHs_MitoticExit_Phos_Silac_IT
Global phosphoproteomic mapping of early mitotic exit in human hela cells, ITCID
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005294 | PeptideAtlas
ProteomicsHs_MitoticExit_Phos_Silac_HCD
Global phosphoproteomic mapping of early mitotic exit in human hela cells, HCD
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005254 | PeptideAtlas
TranscriptomicsBreak-Seq of DNA double stranded breaks in Saccharomyces cerevisiae WT and mec1 cells after exposure to hydroxyurea
We previously demonstrated that inactivation of the replication checkpoint via a mec1 mutation led to chromosome breakage at replication forks initiated from virtually all origins of replication, after transient exposure to hydroxyurea (HU), an inhibitor of ribonucleotide reductase. Furthermore, we...
ORGANISM(S): Saccharomyces cerevisiae 
2015-01-12 | E-GEOD-58808 | biostudies-arrayexpress
TranscriptomicsGenomic Interaction Profiles in Breast Cancer Reveal Altered Chromatin Architecture
Gene transcription can be regulated by remote enhancer regions through chromosome looping either in cis or in trans. Cancer cells are characterized by wholesale changes in long-range gene interactions, but the role that these long-range interactions play in cancer progression and metastasis is not ...
ORGANISM(S): Homo sapiens 
2013-08-03 | E-GEOD-49521 | biostudies-arrayexpress
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