Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of imprint free mouse mouse embryonic stem (IF-ES) cells vs wild type MEFs
Loss of imprinting (LOI), commonly observed in human tumors, refers to loss of monoallelic gene regulation normally conferred by parent-of-origin specific DNA methylation. To test the function of LOI in tumorigenesis, we developed a model using transient demethylation to generate imprint-free mouse ...
ORGANISM(S): Mus musculus 
2005-10-20 | E-MEXP-450 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat kidney samples following treatment with the corticosteroid methylprednisolone over several time intervals
Summary: To identify distinct temporal patterns of mRNA expression in the kidney of rats following a bolus dose of the corticosteroid methylprednisolone. Hypothesis: That prednisone pharmacodynamics can be derived from expression profiling data.
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1721 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of nasal epithelium from CF patients with mild and severe cystic fibrosis lung disease to identify candidate genes that influence the severity of pulmonary disease and to identify genes indicative of CF disease progression
Summary: CF patients homozygous for the DF08 DF08 genotype present a full range of phenotypic manifestations that exist within the pulmonary system. This project aims to identify candidate genes that influence the severity of pulmonary disease; Hypothesis: The goal is to find genes predictive of pro...
ORGANISM(S): Homo sapiens 
2007-10-24 | E-GEOD-2395 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of yeast strains with different chromosome copy numbers
Aneuploidy, the condition of having an abnormal number of chromosomes, is a hallmark of cancer cells. Recent work performed in yeast and mouse models suggests that aneuploidy interferes with cell proliferation and organism development. However, other recent experiments suggested that aneuploidy migh...
ORGANISM(S): Saccharomyces cerevisiae 
2010-10-01 | E-MTAB-318 | biostudies-arrayexpress
TranscriptomicsMapping genetic modifiers of ARPKD
Autosomal recessive polycystic kidney disease (ARPKD) is caused by mutations in the PKHD1 gene in both humans and the orthologous PCK rat model. Although ARPKD results solely from PKHD1 mutations, the disease onset and severity are highly variable, indicating that other unknown genetic risk factor(s...
ORGANISM(S): Rattus norvegicus 
2015-06-06 | E-GEOD-58229 | biostudies-arrayexpress
UnknownPredictors of Current DSM-5 PTSD Diagnosis and Symptom Severity Among Deployed Veterans: Significance of Predisposition, Stress Exposure, and Genetics.
Not available
S-EPMC6956712 | biostudies-literature
UnknownClinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
Not available
S-EPMC6075859 | biostudies-literature
UnknownRisk factors for poor visual outcome in patients with idiopathic intracranial hypertension.
Not available
S-EPMC4553022 | biostudies-literature
UnknownIL10RB as a key regulator of COVID-19 host susceptibility and severity.
Not available
S-EPMC8183086 | biostudies-literature
GenomicsWhole Genome and Exon Capture Sequencing of Bladder Cancers

One primary bladder cancer and paired peripheral blood sample were subjected to whole genome sequencing on an Illumina HiSeq 2000 platform. This technology was utilized to investigate the genetic basis of a durable remission of metastatic bladder cancer in a patient treated with everolimus, a dru...

phs000535.v1.p1 | EGA
Sort   by:  
 Page size