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ProteomicsApocarotenoids are allosteric effectors of a dimeric plant glycosyltransferase involved in plant defense and lignin formation
Glycosyltransferases are Nature’s versatile tools to tailor the functionalities of proteins, carbohydrates, lipids, and small molecules by transferring sugars, while C13-apocarotenoids are oxidative degradation products of carotenoids/xanthophylls that fulfil multiple physiological functions. Here, ...
ORGANISM(S): Nicotiana benthamiana Escherichia coli 
2023-03-30 | PXD035955 | Pride
Phytoalexin Activation Glycosyltransferase Ionol Lignin Apocarotenoids 
ModelsBurbano2023 - HGFsignaling_in_FattyLiverDisease
Chronic liver diseases are worldwide on the rise. Due to the rapidly increasing incidence, in particular in Western countries, non-alcoholic fatty liver disease (NAFLD) is gaining importance. As the disease progresses it can develop into hepatocellular carcinoma. Lipid accumulation in hepatocytes ha...
2025-03-24 | BIOMD0000001102 | BioModels
ProteomicsTruncated N-glycans destabilize POMT1 and POMT2 but do not limit cellular O-mannosylation in HEK293 cells
Protein O-mannosylation is initiated by the ER-resident enzymes POMT1 and POMT2, both of which carry multiple N-glycans essential for proper folding and activity. Although congenital disorders of glycosylation type I (CDG-I) disrupt the early N-glycosylation process, their impact on POMT biogenesis ...
ORGANISM(S): Homo Sapiens 
PXD073179 | panorama
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