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The trade-off between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identif...
2022-02-28 | MTBLS2334 | MetaboLights
Precise assignment of sialylation linkages at the glycopeptide level is of importance in bottom-up glycoproteomics, and is also an indispensable step to understand the function of glycoproteins in pathogen-host interactions and cancer progression. Even though some efforts have been dedicated to the ...
ORGANISM(S): Homo sapiens (Human) 
2020-04-21 | PXD016151 | Pride
Glycosyltransferases are Nature’s versatile tools to tailor the functionalities of proteins, carbohydrates, lipids, and small molecules by transferring sugars, while C13-apocarotenoids are oxidative degradation products of carotenoids/xanthophylls that fulfil multiple physiological functions. Here, ...
ORGANISM(S): Nicotiana benthamiana Escherichia coli 
2023-03-30 | PXD035955 | Pride
Glioblastoma (GBM) is the most aggressive primary brain tumor characterized by infiltrative migration of malignant glioma cells into the surrounding brain parenchyma. In this study, our analysis of GBM patient cohorts displayed significant higher expression of Glycosyltransferase 8 domain containing...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD027854 | Pride
Genomics
Investigation of Glycosyltransferase Sequence
Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity
Glycosyltransferase Extl1 promotes CCR7-mediated dendritic cell migration to restrain infection and autoimmunity

Flavonoids are specialized metabolites that play important roles in plants, including interactions with the environment. The high structural diversity of this metabolite group is largely due to enzyme-mediated modifications of flavonoid core skeletons. In particular, glycosylation with different ...

2025-02-25 | MTBLS1965 | MetaboLights
Purpose: mRNAs sequencing of the gene expression differences in LPS-stimulated Extl1-dificient mDC and wild-type mDC. The goals of this study are to investigate the biological effect of glycosyltransferase Extl1 in regulating dendritic cell function.
ORGANISM(S): Mus musculus 
2023-01-19 | GSE184976 | GEO
In order to investigate glycosyltransferase enzyme GCNT3 function and to identify putative GCNT3 partners, regulators and/or downstream targets, we performed genomic analysis of GCNT3 overexpression in colon cancer cells. Data from three independent experiments were assayed in a whole genome microar...
ORGANISM(S): Homo sapiens 
2017-06-12 | GSE88792 | GEO
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