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Head and neck squamous cell carcinomas (HNSCC) are highly immunosuppressive, and tumor-associated macrophages comprise a major part in HNSCC tumor microenvironments. Here, we investigate the effects induced by small extracellular vesicles (sEVs) of HNSCC patients on primary macrophages. sEVs were is...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD069623 | Pride
In lymphomas derived from mature B cells the expression of the transcription factor PAX5 is maintained whereas classical Hodgkin lymphoma displays significantly reduced PAX5 expression despite its derivation from mature B cells. To elucidate the functional role of PAX5 in classical Hodgkin lymphoma,...
ORGANISM(S): Homo sapiens 
RNA-sequencing data from teh hT-RPE-MycER cell line after MYC activation and after MINCR knock-down in conditions of MYC ON or OFF
Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long non-coding RNAs (lncRNAs), on the way MYC is able to influence cellular transcriptome. To this aim we have intersected RNA-sequencing data f...
Despite the established role of the transcription factor MYC in cancer, little is known about the involvement of lncRNAs in mediating MYC’s function. Here we have intersected RNA-sequencing data from MYC-inducible cell lines, from a cohort of 91 mature B-cell lymphomas and from sorted germinal-cente...
Data Access Committee EGAC00001000381
PAR-CLIP was performed on the Argonaute-2 protein (AGO2) in four lymphoma cell lines: Namalwa Raji SU-DHL-4 SU-DHL-6
Part of WGS seq data of Maligant Lymphoma study (ICGC)
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