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TranscriptomicsClariomS Array to determine the impact of whole body adenylyl cyclase 5 (Adcy5) knockout on male/female epigonadal white adipos tissue (eWAT) gene expression
We analyzed the effect of whole body Adcy5 knockout on adipose tissue gene expression profiles. Therefore, we isolated RNA, examined RNA integrity and concentration on an Agilent Fragment Analyzer using the HS RNA Kit. cRNA was prepared from 100 ng of total RNA hybridized to GeneChip Clariom S array...
ORGANISM(S): Mus musculus 
2021-04-19 | E-MTAB-9417 | biostudies-arrayexpress
ProteomicsNon-labelled proteomics expression analysis of PC-3 cells treated with transferrin conjugated gold nanoparticles
Nanoparticles-based therapeutics are being clinically translated for treating cancer. Meanwhile nanoparticles are increasingly being identified as impacting cell regulation and protein expression. Here, we sought to understand how a model of a relatively inert nanoparticle without any therapeutic ag...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039433 | Pride
Antioxidant Proteomics Tem Reactive oxygen species Nanoparticle Glutathione-thioredoxin 
TranscriptomicsA549 Sagopilone
Anticancer drug sagopilone in lung cancer line A549. We performed gene expression analysis of lung cancer cell line A549 treated with sagopilone and paclitaxel. The aim was to analyse gene expression differences between the two drugs in two different concentrations. A549 cells were treated with medi...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-MTAB-377 | biostudies-arrayexpress
UnknownKinetic Effects of Transferrin-Conjugated Gold Nanoparticles on the Antioxidant Glutathione-Thioredoxin Pathway.
Not available
S-EPMC10451790 | biostudies-literature
TranscriptomicsSMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
Characterization of the selectivity of SMN splicing modifiers in SMA type I fibroblasts by RNASeq In total 12 samples were analyzed, divided into four distinct groups (treated with SMN-C3 @ 500 nM; controls for SMN-C3; treated with SMN-C1 @ 100 nM; controls for SMN-C1) containing 3 replicates each.
ORGANISM(S): Homo sapiens 
2014-10-22 | E-GEOD-62540 | biostudies-arrayexpress
ProteomicsComparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis.
This study represents a proteomic resource for HNSCC and SQCLC with quantitative protein expression data for 7800 proteins and provides a proteomic diagnostic signature for classification for undetermined secondary lung tumors in HNSCC patients. By quantitative mass-spectrometry-based proteomics, we...
ORGANISM(S): Homo sapiens (Human) 
2018-08-06 | PXD007705 | Pride
Head and neck cancer Human tissue proteomics Lung cancer Squamous cell carcinoma Diagnostic biomarker Metastasis 
UnknownEvaluation of the effectiveness of a nationwide precision medicine program for patients with advanced non-small cell lung cancer in Germany: a historical cohort analysis.
Not available
S-EPMC10687333 | biostudies-literature
UnknownNeutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study.
Not available
S-EPMC9757903 | biostudies-literature
UnknownNRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo
Not available
S-SCDT-10_1038-S44318-025-00520-2 | biostudies-other
UnknownComparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis.
Not available
S-EPMC6127892 | biostudies-literature
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