Hoffmann Stefan A SA

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Unknown (6)
Genomics (5)
Metabolomics (1)
Proteomics (1)

Organisms

Homo sapiens (6)

Repository

EGA (5)
MetaboLights (1)
pride (1)

Technology Type

Illumina HiSeq 2000, Affymetrix SNP 6.0 (1)
Mass spectrometry (1)
Data-dependent acquisition (1)
Mass Spectrometry (1)

Instrument Platform

Autoflex speed smartbeam (1)

Publication Date

2016 (1)
2025 (1)

Metabolite Name

(+)-Syringaresinol O-beta-D-glucoside (1)
(+)-secoisolariciresinol diglucoside (1)
(-)-11-hydroxy-9,10-dihydrojasmonic acid 11-beta-D-glucoside (1)
(-)-Columbianetin (1)
(-)-Epigallocatechin 3-gallate 7-glucoside 4"-glucuronide (1)
(-)-Jasmonic acid (1)
(-)-epicatechin (1)
(15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate (1)
(2S)-2-Butanol O-[b-D-Apiofuranosyl-(1->6)-b-D-glucopyranoside] (1)
(2S)-2-hydroxybutanedioic acid (1)
(2b,3b)-Dihydroxy-30-nor-12,20(29)-oleanadiene-28-glucopyranosyloxy-23-oic acid 3-glucuronide (1)
(6Z,9Z,12Z)-Octadecatrienoic acid (1)
(7'R)-(+)-Lyoniresinol 9'-glucoside (1)
(9R,10R)-Dihydroxyoctadecanoic acid (1)
(9Z)-(7S,8S)-Dihydroxyoctadecenoic acid (1)
(9Z)-Hexadecenoic acid (1)
(9Z)-Octadecenoic acid (1)
(9Z,12Z)-(8R)-Hydroxyoctadeca-9,12-dienoic acid (1)
(R)-(Homo)3-citrate (1)
(R)-1-O-[b-D-Glucopyranosyl-(1->6)-b-D-glucopyranoside]-1,3-octanediol (1)
(R)-5-Phosphomevalonate (1)
(S)-Malate (1)
(S)-Multifidol 2-[apiosyl-(1->6)-glucoside] (1)
(Z)-Resveratrol 3,4-diglucoside (1)
1,5-Dihydroxy-4,8-bis(hydroxy(hydroxymethyl)amino)anthraquinone (1)
1,8-Diazacyclotetradecane-2,9-dione (1)
1-Caffeoyl-4-deoxyquinic acid (1)
1-O-Galloyl-beta-D-glucose (1)
1-O-Sinapoyl-beta-D-glucose (1)
1-Octen-3-ol-3-o-beta-D-xylopyranosyl(1->6)-beta-D-glucopyranoside (1)

Release Date

2022 (2)
2021 (2)
2024 (1)
2020 (1)

Lab affiliation

Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany Structural Genomics Consortium (SGC), Buchmann Institute for Life Sciences, Max-von-Laue-Str. 15, 60438 Frankfurt am Main, Germany (1)

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A general workflow for E3 ligase ligand validation for PROTAC development

PROteolysis TArgeting Chimeras (PROTACs) have gained considerable attention as a new modality in drug discovery. However, the development of PROTACs has been mainly focused on CRBN (Cereblon) and VHL (van Hippel-Lindau Ligase) ligands. The considerable size of the human E3 ligase family, newly devel...

ORGANISM(S): Homo sapiens (Human)

2025-04-04 | PXD057431 | Pride

Benchmark datasets for 3D MALDI- and DESI-Imaging Mass Spectrometry

Three-dimensional imaging mass spectrometry (3D imaging MS) is a technique of analytical chemistry for 3D molecular analysis of a tissue specimen, entire organ, or microbial colonies on an agar plate. 3D imaging MS has unique advantages over existing 3D imaging techniques, offers novel perspectives ...

2016-07-27 | MTBLS176 | MetaboLights

ena-DATASET-RTL-06-02-2015-14:59:15:066-180 - samples

RNA-sequencing (RNA-seq) was performed with RNA extracted from fresh-frozen human tumor tissue samples. cDNA libraries were prepared from poly-A selected RNA applying the Illumina TruSeq protocol for mRNA. The libraries were then sequenced with a 2 x 100bp paired-end protocol to a minimum mean cover...

EGAD00001001244 | EGA

ena-DATASET-RTL-11-03-2015-12:07:49:303-16 - samples

Whole genome sequencing was performed with DNA extracted from fresh-frozen tumor and normal material. Short insert DNA libraries were prepared with the TruSeq DNA PCRfree sample preparation kit (Illumina) for paired-end sequencing at a minimum read length of 2x100bp. Human DNA libraries were sequenc...

EGAD00001001273 | EGA

Comprehensive genomic profiles of small cell lung cancer

We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...

EGAS00001000925 | EGA

SCLC_SNP_6.0 - samples

SNP 6.0 arrays of small cell lung cancer

EGAD00010000558 | EGA

DAC University of Cologne

Data Access Committee EGAC00001000064

EGAC00001000064 | EGA

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.

Not available

S-EPMC12056793 | biostudies-literature

Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses.

Not available