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MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsTranscriptomic responses to salinity stress in invasive and native blue mussels (genus Mytilus)
The invasive marine mussel Mytilus galloprovincialis has displaced the native congener Mytilus trossulus from central and southern California, but the native species remains dominant at more northerly sites that have high levels of freshwater input. To determine the extent to which interspecific dif...
ORGANISM(S): Mytilus galloprovincialis 
2011-01-10 | E-GEOD-25111 | biostudies-arrayexpress
UnknownA taxogenomic view of the genus <i>Torulaspora</i>: an expansion from ten to twenty-two species.
Not available
S-EPMC12308288 | biostudies-literature
UnknownPartially fluorinated copolymers containing pendant piperidinium head groups as anion exchange membranes for alkaline fuel cells.
Not available
S-EPMC9075601 | biostudies-literature
UnknownAge constraints for the Trachilos footprints from Crete.
Not available
S-EPMC8505496 | biostudies-literature
TranscriptomicsBulk RNA-sequencing of testes and kidneys from wildtype and Gfi1[R412X] embryonic mice
Embryonic (E17.5) testes and kidneys from wildtype or Gfi1[R412X] mice, a model of severe congenital neutropenia, were analyzed by bulk RNA-sequencing.
ORGANISM(S): Mus musculus 
2026-06-09 | E-MTAB-15317 | biostudies-arrayexpress
GenomicsDNA methylation changes are a late event in Acute Promyelocytic Leukemia and coincide with loss of transcription factor binding (sequencing)
The origin of aberrant DNA methylation in cancer remains largely unknown. In this study, we elucidated the DNA methylome in primary Acute Promyelocytic Leukemia (APL) and the role of PML-RARa in establishing these patterns. APL patients showed increased genome-wide DNA methylation with higher variab...
ORGANISM(S): Homo sapiens 
2012-11-08 | E-GEOD-42044 | biostudies-arrayexpress
MetabolomicsLipid Droplet Inhibitors for Disrupting Lipid Accumulation in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Excessive lipid droplet accumulation in hepatocytes drives the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), often leading to inflammation and fibrosis. As obesity and metabolic syndrome rise, MASLD has become a global concern, spurring research into effective trea...
2025-07-17 | MTBLS12359 | MetaboLights
TranscriptomicsscRNA-sequencing of embryonic and neonatal immune cells isolated from various organs
Immune cells were isolated from hematopoietic and non-hematopoietic tissues from fetal and newborn mice and analyzed by scRNA-sequencing.
ORGANISM(S): Mus musculus 
2026-06-09 | E-MTAB-15320 | biostudies-arrayexpress
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