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MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownTetrakis-Cyanoacetylides as Building Blocks for a Second Generation of Spin-Switchable Hofmann-type Networks with Enhanced Porosity.
Not available
S-EPMC11409210 | biostudies-literature
UnknownUndifferentiated spermatogonia regulate Cyp26b1 expression through NOTCH signaling and drive germ cell differentiation.
Not available
S-EPMC6593872 | biostudies-literature
UnknownEnhanced Interplay between Host-Guest and Spin-Crossover Properties through the Introduction of an N Heteroatom in 2D Hofmann Clathrates.
Not available
S-EPMC9490864 | biostudies-literature
UnknownRelease of protein N-glycans by effectors of a Hofmann carboxamide rearrangement.
Not available
S-EPMC9512068 | biostudies-literature
UnknownSymmetry Breaking and Cooperative Spin Crossover in a Hofmann-Type Coordination Polymer Based on Negatively Charged {FeII(μ2-[MII(CN)4])2}n2n- Layers (MII = Pd, Pt).
Not available
S-EPMC10428219 | biostudies-literature
UnknownThermo- and photo-modulation of exciplex fluorescence in a 3D spin crossover Hofmann-type coordination polymer.
Not available
S-EPMC6247521 | biostudies-literature
TranscriptomicsExtraction of Total RNA from Single Neurons: Mauthner-cell Cytoplasm vs. Whole Brain
Astatotilapia burtoni males change their startle behavior in accordance with changes in a socially-mediated phenotypic state. When dominant (DOM), males are brightly colored, isolated from the school and startle readily in response to an auditory pulse. When subordinate (SUB), males are cryptically ...
ORGANISM(S): Haplochromis burtoni 
2010-12-23 | E-GEOD-26277 | biostudies-arrayexpress
TranscriptomicsTranscriptomic responses to salinity stress in invasive and native blue mussels (genus Mytilus)
The invasive marine mussel Mytilus galloprovincialis has displaced the native congener Mytilus trossulus from central and southern California, but the native species remains dominant at more northerly sites that have high levels of freshwater input. To determine the extent to which interspecific dif...
ORGANISM(S): Mytilus galloprovincialis 
2011-01-10 | E-GEOD-25111 | biostudies-arrayexpress
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