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GenomicsHog1 controls global reallocation of RNA Pol II upon osmotic shock
When challenged with osmotic shock, S. cerevisiae induces hundreds of genes, despite a global reduction in transcriptional capacity. The mechanisms that regulate this rapid reallocation of transcriptional resources are not known. Here we show that redistribution of RNA Pol II upon stress requires ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-15 | E-GEOD-38208 | biostudies-arrayexpress
TranscriptomicsContribution of the Hog1 SAPK to nitrosative stress response in Candida albicans.
RNA sequencing was performed on Candida albicans wild type cells (JC50) grown to exponential phase on YPD , YPD plus Nitrosative Stress 2.5mM DPTA NONOate, and compared to exponential Candida albicans hog1 deletion mutant cells grown on on YPD , YPD plus Nitrosative Stress 2.5mM DPTA NONOate. Three...
ORGANISM(S): Candida albicans 
2018-03-02 | E-MTAB-5990 | biostudies-arrayexpress
TranscriptomicsNuclear Localization of Hog1 MAPK is Not Necessary for Resistance to Hyperosmotic Stress
In budding yeast, this signaling pathway— the high-osmolarity glycerol (HOG) response —culminates in dual phosphorylation and nuclear translocation of the MAPK, Hog1 (ortholog of mammalian p38/SAPK). Induction of at least 50 genes requires nuclear Hog1, implying that transcriptional up-regulation...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-01 | E-GEOD-8703 | biostudies-arrayexpress
TranscriptomicsStructure and Function of a Transcriptional Network Activated by Hog1
Cells regulate gene expression using a complex network of signaling pathways, transcription factors and promoters. To gain insight into the structure and function of these networks we analyzed gene expression in single and multiple mutant strains to build a quantitative model of the Hog1 MAPK-depen...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12270 | biostudies-arrayexpress
TranscriptomicsHog1 ChIP Chip
Yeast Hog1-3HA ChIP-Chip in triplicate Keywords: ChIP-Chip Yeast Hog1 ChIP-Chip was performed in MAP51 (3HA-Hog1) in triplicate using anti-HA (12CA5 monoclonal antibody)
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-01 | E-GEOD-4862 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and hog1 Candida albicans subjected to environmental stresses that are known to activate the Hog1 Stress-activated Protein Kinase
Based on studies in S. pombe (Chen et al., 2003), we predicted that conditions which activate C. albicans Hog1 would result in the induction of a common set of genes that are regulated by this SAPK (Smith et al., 2004). Hence in this study we compared the global transcriptional responses of wild-typ...
ORGANISM(S): Candida albicans 
2007-07-05 | E-MEXP-1134 | biostudies-arrayexpress
Transcriptomicshog1 mutant 3 hour exposure to zymolyase
We did transcription profiling on the effect of hog1 deletion, gene involved in cell osmotic stress and cell wall stress response Keywords: cell wall stress response S. cerevisiae (hog1 mutant) was grown on YEPD. For Zymolyase experiments, yeast cells were grown overnight at 24 °C to an optical den...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-9931 | biostudies-arrayexpress
GenomicsStudy gene expression specifically regulated by intrinsically active HOG1
Study gene expression specifically regulated by intrinsically active HOG1
PRJNA420362 | ENA
ProteomicsThiol-Based Direct Threat Sensing by the Stress-Activated Protein Kinase Hog1
The stress-activated protein kinase Hog1 is best known for its role in osmotic stress but is also activated by a variety of mechanistically distinct environmental stressors including heat shock, ER stress, and arsenic. In the osmotic stress response, the signal is sensed upstream and relayed to Hog1...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-12-04 | PXD015325 | Pride
Arsenic stress Yeast Tmt 
Transcriptomicshog1, slt2, rlm1, and msn2/4 mutants exposed to zymolyase
This SuperSeries is composed of the following subset Series: GSE9930: Wild type 3 hour exposure to zymolyase GSE9931: hog1 mutant 3 hour exposure to zymolyase GSE9932: slt2 mutant 3 hour exposure to zymolyase GSE9933: rlm1 mutant 3 hour exposure to zymolyase GSE9934: msn2/4 mutant 3 hour exposure to...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-19 | E-GEOD-12684 | biostudies-arrayexpress
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