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MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
UnknownGenome-wide effect of pulmonary airway epithelial cell-specific <i>Bmal1</i> deletion.
Not available
S-EPMC6463917 | biostudies-literature
UnknownDeciphering the Duality of Clock and Growth Metabolism in a Cell Autonomous System Using NMR Profiling of the Secretome.
Not available
S-EPMC5041122 | biostudies-literature
TranscriptomicsLarge-scale analysis of the human transcriptome - Novartis dataset
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-12-06 | E-GEOD-96 | biostudies-arrayexpress
TranscriptomicsCircadian liver_wt and Clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-3748 | biostudies-arrayexpress
UnknownGenome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.
Not available
S-EPMC555478 | biostudies-literature
TranscriptomicsComparative Analysis of RNA-Seq Alignment Algorithms and the RNA-Seq Unified Mapper (RUM).
A critical task in high throughput sequencing is aligning millions of short reads to a reference genome. Alignment is especially complicated for RNA sequencing (RNA-Seq) because of RNA splicing. A number of RNA-Seq algorithms are available, and claim to align reads with high accuracy and efficiency ...
ORGANISM(S): Mus musculus 
2011-08-03 | E-GEOD-26248 | biostudies-arrayexpress
UnknownClock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.
Not available
S-EPMC5479132 | biostudies-literature
UnknownThe transcription factor encyclopedia.
Not available
S-EPMC3439975 | biostudies-literature
UnknownLong-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP).
Not available
S-EPMC7279201 | biostudies-literature
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