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ProteomicsSite-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling
HOIP, the catalytic component of the Linear Ubiquitin chain Assembly Complex (LUBAC), is a critical regulator of inflammation. However, how HOIP itself is regulated to control inflammatory responses is unclear. Here, we discover that site-specific ubiquitination of K784 within HOIP promotes Tumour N...
ORGANISM(S): Homo sapiens (Human) 
2020-08-31 | PXD021217 | Pride
Site-specific ubiquitination of the e3 ligase hoip regulates apoptosis and immune signaling 
GenomicsTranscriptional analysis of whole blood and PBMCs from human HOIP deficiency patients
Transcriptional analysis of whole blood and PBMCs from human HOIP deficiency patients
PRJNA487219 | ENA
ProteomicsAnalysis of the TNFR1-SC from HOIP-proficient and -deficient A549 cells
This study aimed at determining which components of the TNFR1-SC are recruited in dependency of HOIP.
ORGANISM(S): Homo sapiens (Human) 
2018-09-25 | PXD008497 | Pride
Ap-ms Tnfr1-sc Hoip 
TranscriptomicsTranscriptional analysis of whole blood and PBMCs from human HOIP deficiency patients
LUBAC (linear ubiquitin assembly complex) consists of HOIP, HOIL1 and SHARPIN. HOIP deficiency has been characterized by immunodeficiency, autoinflammation and amylopectinosis. To explore the molecular mechanism of the autoinflammation, we performed a transcriptome-wide analysis using whole blood an...
ORGANISM(S): Homo sapiens 
2018-08-23 | GSE118901 | GEO
GenomicsEffect of depletion of HOIP on gene expression during B16-F10 melanoma tumor development in immunedeficinet mice.
Effect of depletion of HOIP on gene expression during B16-F10 melanoma tumor development in immunedeficinet mice.
PRJNA851045 | ENA
GenomicsGlobal gene expression in human T cells with targeted disruption of TRAF6 or HOIP
Global gene expression in human T cells with targeted disruption of TRAF6 or HOIP
PRJNA1277211 | ENA
GenomicsEffect of TRIP12, UBR5, or HOIP in gene expression
Effect of TRIP12, UBR5, or HOIP in gene expression
PRJNA1209928 | ENA
UnknownE3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.
Not available
S-EPMC3990471 | biostudies-literature
UnknownSite-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.
Not available
S-EPMC7737615 | biostudies-literature
UnknownSystematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
Not available
S-EPMC10998861 | biostudies-literature
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