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ProteomicsIdentification of interaction partners of novel polyacetylene
To elucidate molecular interaction partners of a novel plant-derived polyacetylene, we used a biotin-labelled polyacetylene in two cell lines (HEK293 and HepG2) and performed biotin-pulldown assays and proteomic analyses via LC-MSMS.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD037671 | Pride
Lc-msms Biotin-label compound Human cell lines 
ProteomicsExploration of human cerebrospinal fluid: A large proteome dataset revealed by trapped ion mobility time-of-flight mass spectrometry
Cerebrospinal fluid (CSF) is a biofluid in direct contact with the brain and as such constitutes a sample of choice in the study of neurological disorders, including neurodegenerative diseases such as Alzheimer or Parkinson. Human CSF has still been less studied using proteomic technologies compared...
ORGANISM(S): Homo sapiens (Human) 
2020-05-07 | PXD018369 | Pride
Proteomics Mass spectrometry Large-scale proteome Cerebrospinal fluid Lc-ms/ms 
ProteomicsAllogeneic antibodies specifically target AML antigen NuSAP1 after bone marrow transplantation
Identifying the targets of immune response after allogeneic hematopoietic cell transplantation (HCT) promises to provide relevant immune therapy candidate proteins. We used protein microarrays to serologically identify Nucleolar and Spindle Associated Protein 1 (NuSAP1) and Chromatin Assembly Factor...
ORGANISM(S): Homo sapiens 
2010-06-21 | E-GEOD-15255 | biostudies-arrayexpress
ProteomicsDysregulated Hippocampal Fatty Acid Metabolism Following Intermittent Hypoxemia-induced Neonatal Brain Injury is Rescued by Treatment with Acetate – Normoxia vs Intermittent Hypoxia – Sex Difference Analysis
The brain is a lipid-rich organ that experiences rapid growth and development after birth in a period hallmarked by extensive lipid synthesis. We still lack a fundamental understanding of lipid metabolism during this critical time of brain development and how these dynamics occur in infants born ext...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-20 | PXD070491 | Pride
Hippocampus Tmt Orbitrap Mouse Neonatal brain injury Intermittent hypoxia 
TranscriptomicsMouse feeding experiment
Mice used in this study were 129/sv males, 8-15 weeks of age, which were housed individually and received water ad libitum. Normal fed animals were fed before and during the 48h experiment with standard food ad libitum. Sugar fed animals were fed before the experiment with standard food ad libitum a...
ORGANISM(S): Mus musculus 
2004-02-08 | E-GEOD-858 | biostudies-arrayexpress
TranscriptomicsMicroarray (one-color) gene expression analysis of Euglena gracilis subjected to altered acceleration during parabolic flight
Euglena gracilis is a unicellular freshwater flagellate, which uses the gravitational vector for orientation in the water column in the dark. This allows the cell to reach areas in the water column for reproduction and growth. How exactly the gravitational vector is perceived, and which intracellula...
ORGANISM(S): Euglena gracilis 
2019-07-09 | E-MTAB-8064 | biostudies-arrayexpress
ProteomicsAn isobaric labeling approach to enhance detection and quan-tification of tissue-derived plasma proteins as potential early disease biomarkers
Accurate detection and quantification of low abundance proteins by standard mass spectrometry approaches remains challenging. In addition, it is difficult to link low abundance plasma proteins back to their specific tissues or organs of origin with confidence. To address these challenges, we develop...
ORGANISM(S): Papio anubis anubis Papio hamadryas adenovirus 1 
2023-03-11 | PXD039430 | Pride
Lc-msms Kidney Tmt Plasma 
TranscriptomicsExposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
Six to eight week old female C57BL/6J mice were exposed to 2 Gy of whole body γ radiation and mammary glands were surgically removed 2-month after radiation. RNA was isolated and microarray hybridization performed for gene expression analysis. 5 samples were analyzed: 2 controls at 2 months, 1 2 Gy ...
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-57196 | biostudies-arrayexpress
UnknownELM-the Eukaryotic Linear Motif resource-2024 update.
Not available
S-EPMC10767929 | biostudies-literature
TranscriptomicsTranscription profiling of B7.5 lineage cells in the tunicate Ciona intestinalis to study cardiac cell migration
Eight different types of sample (three samples each) were used in this study of cardiac cell migration in the tunicate Ciona intestinalis. The B7.5 lineage cells were isolated by Fluorescent Activated Cell Sorting (FACS) at the tailbud stage, when the cardiac precursors (anterior B7.5 lineage cells)...
ORGANISM(S): Ciona intestinalis 
2008-06-01 | E-MEXP-1478 | biostudies-arrayexpress
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