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ProteomicsA Proteomic Approach to Understanding the Pathogenesis of Idiopathic Macular Hole Formation
Idiopathic macular holes (IMH) are full-thickness defects of retinal tissue that cause severe vision loss due to disruption of the anatomic fovea. Abnormal vitreous traction is involved in the formation of macular holes. Both glial cells and hyalocytes contribute to epiretinal membrane formation in ...
ORGANISM(S): Homo sapiens (Human) 
2018-04-11 | PXD006687 | Pride
Eye Proteomics Vitreous Idiopathic macular hole Retina 
UnknownAugmenting biologging with supervised machine learning to study in situ behavior of the medusa Chrysaora fuscescens.
Not available
S-EPMC6739807 | biostudies-literature
UnknownA novel familial mutation in the PCSK1 gene that alters the oxyanion hole residue of proprotein convertase 1/3 and impairs its enzymatic activity.
Not available
S-EPMC4182778 | biostudies-literature
TranscriptomicsAge-related vascular remodeling in bone marrow
This dataset comprises a bulk transcriptomic profile of bone marrow flush from tibia of C57BL/6N mice. Differential gene expression analysis was performed comparing old (67-71-week-old; n = 3 males and 3 females) versus young (8-week-old; n = 3 males and 3 females) mice. Data was generated separat...
ORGANISM(S): Mus musculus 
2025-11-23 | E-MTAB-15951 | biostudies-arrayexpress
UnknownTestosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells.
Not available
S-EPMC3602280 | biostudies-literature
UnknownDegradation in carbon stocks near tropical forest edges.
Not available
S-EPMC4703854 | biostudies-literature
ProteomicsPacific Ocean metaproteomics, METZYME KM1128
Global metaproteomic analyses of microbial biomass from the upper water column of the Central Pacific Ocean. This dataset was used as a discovery dataset to identify peptide biomarkers for cyanobacterial populations for use in targeted metaproteomic calibrated multiple reaction monitoring (MRM) anal...
ORGANISM(S): Environmental Samples (ncbitaxon:318178) 
2021-11-05 | MSV000088323 | MassIVE
TranscriptomicsTranscriptome profiling in 6-hydroxydopamine hemiparkinsonian rats reveals methamphetamine-mediated dopamine-independent changes in striatal gene expression.
Unilateral injections of 6-hydroxydopamine into the medial forebrain bundle (MFB) is used extensively as a model of Parkinson’s disease. The present experiments examined whether a single injection of methamphetamine (METH) (2.5 mg/kg) could still influence striatal gene expression after 6-hydroxydop...
ORGANISM(S): Rattus norvegicus 
2010-09-21 | E-GEOD-24233 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thermosensitive exosome mutants from permissive temperature and various time exposure to restrictive temperature
Transcriptome analyses of thermosensitive exosome mutants from permissive temperature to various time exposure to restrictive temperature.
ORGANISM(S): Saccharomyces cerevisiae 
2006-02-28 | E-MEXP-537 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of late exponential vs. stationary phase cultures using a custom designed Pseudo-nitzschia multiseries (Ps-n) cDNA microarray
Pseudo-nitzschia multiseries (Ps-n) is a toxigenic marine diatom that produces the neurotoxin, domoic acid. We screened for candidate genes that may be involved in domoic acid production by determining changes in transcript profiles in Ps-n cultures that were in late exponential (low-domoic-acid-pro...
ORGANISM(S): Pseudo-nitzschia multiseries 
2013-09-08 | E-GEOD-46845 | biostudies-arrayexpress
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