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ProteomicsCharacterization of the Cardiac Myosin Binding Protein-C Phosphoproteome in Healthy and Failing Human Hearts
Introduction: Cardiac myosin binding protein-C (cMyBP-C) becomes dephosphorylated in the failing heart and reduced phosphorylation-dependent regulation of cMyBP-C has been implicated in contractile dysfunction. To date, several phosphorylation sites have been identified for human cMyBP-C; however, ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2013-05-01 | PXD000158 | Pride
Phosphoprotein Phosphoproteome Mass spectrometry Cardiac myosin binding protein c Cmybpc Cardiac 
ProteomicsA novel phosphorylation site at Ser130 adjacent to the pseudosubstrate domain regulates protein kinase C-δ activity
Protein kinase C over-expressed into rat neonatal myocytes were lysed in 8M Urea, 0.1% SDS and trypsin digested. Peptides were fractionated by SPE-SCX and enriched by TiO2. Phosphopeptides were analyzed by LC/MS on a Thermo LTQ Elite Orbitrap. Raw files were searched using Sorcerer-Sequest and pos...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-10-24 | PXD002536 | Pride
Phosphorylation Pkc Protein kinase c 
ProteomicsHs_Albuminome_Serum
Albuminome from human serum
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005187 | PeptideAtlas
ProteomicsHs_Albuminome_CSF
Albuminome from human CSF
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe005108 | PeptideAtlas
ProteomicsIdentification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes
Coronary artery disease remains a leading cause of death in industrialized nations, and early detection of disease is a critical intervention target in order to effectively treat patients and manage risk. Proteomic analysis of mixed tissue homogenates may obscure subtle protein changes that occur un...
ORGANISM(S): Homo Sapiens 
2021-01-21 | PXD016730 | panorama
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