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ProteomicsProteomic Analysis of Integrin a5 Associated Complexes Dependent upon Integrin Activation State in Zebrafish
Integrins are a major class of heterodimeric adhesion receptors composed of an a and b subunit that link the extracellular matrix (ECM) and the cytoskeleton across the cell membrane. When activated by either the intracellular (inside-out signaling) or extracellular (outside-in signaling) environment...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2021-05-27 | PXD024942 | Pride
Integrin activation Lc-msms 12 somite stage Integrin a5 Zebrafish Cell adhesion Extracellular matrix 
ProteomicsIntegrin a5, aV, and aVb3 in zebrafish embryos at the 12 somite stage
Integrins are a major class of heterodimeric adhesion receptors composed of an a and b subunit that mediate cell adhesion to the extracellular matrix (ECM). The extracellular matrix protein fibronectin is important for early vertebrate development, and Integrin a5b1 and aVb3 are the two primary fibr...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2021-09-10 | PXD024665 | Pride
Lc-msms Integrin 12 somite stage Zebrafish Extracellular matrix 
ProteomicsProteomic Analysis of Integrin a5 Associated Complexes Dependent upon Integrin Activation State in Zebrafish
Integrins are a major class of heterodimeric adhesion receptors composed of an a and b subunit that link the extracellular matrix (ECM) and the cytoskeleton across the cell membrane. When activated by either the intracellular (inside-out signaling) or extracellular (outside-in signaling) environment...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-10-13 | PXD065495 | Pride
Integrin activation Lc-msms 12 somite stage Integrin a5 Zebrafish Cell adhesion Extracellular matrix 
ProteomicsTargeted mass spectrum on activation-state-dependent Integrin alpha 5
Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio Rerio 
2025-11-10 | PXD058747 | panorama
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