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TranscriptomicsAI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro
This SuperSeries is composed of the following subset Series: GSE18427: Addition of Exogenous AI-2 to C. jejuni 11168 Wild Type and LuxS01. GSE18451: Wild Type 11168 versus LuxS01 Mutant Cultured in MHB and MEM- ? media Refer to individual Series
ORGANISM(S): Campylobacter jejuni 
2009-10-08 | E-GEOD-18455 | biostudies-arrayexpress
MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
TranscriptomicsWild Type 11168 versus LuxS01 Mutant Cultured in MHB and MEM- α media
Transcriptional profiling of Campylobacter jejuni NCTC 11168 wild type versus LuxS01 mutant strain grown in a minimal culture medium (MEM- α ) versus complex culture medium (MHB). Two-condition experiment, the parent versus the mutant 11168 strains were grown in 2 types of culture medium for compar...
ORGANISM(S): Campylobacter jejuni 
2010-06-21 | E-GEOD-18451 | biostudies-arrayexpress
TranscriptomicsAddition of Exogenous AI-2 to C. jejuni 11168 Wild Type and LuxS01.
Transcriptional profiling of Campylobacter jejuni NCTC 11168 wild type and LuxS01 mutant strains comparing the effects of exogenously added in vitro-produced autoinducer 2 (AI-2) versus a control buffer to both strains. Two-condition experiment, addition of exogenous AI-2 to both the parent and muta...
ORGANISM(S): Campylobacter jejuni 
2010-06-21 | E-GEOD-18427 | biostudies-arrayexpress
TranscriptomicsWhole Genome Sequencing Informs Therapeutic Selection for Pancreatic Cancer
Pancreatic cancer remains one of the most lethal of malignancies and a major health burden. We performed whole genome sequencing and CNV analysis of 100 pancreatic ductal adenocarcinomas. Chromosomal rearrangements leading to gene disruption were frequent, affecting genes known to be important in pa...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-61502 | biostudies-arrayexpress
UnknownTIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells.
Not available
S-EPMC7148170 | biostudies-literature
TranscriptomicsControl vs hyper; 25 mM glucose_Filtered fb-bg
Transcriptional analysis upon the overexpression of the folate gene cluster on a high copy plasmid when compared to an empty vector in the lactic acid bacterium L. plantarum. The transcriptional response was determined for both strains in continuous culture in the presence of glucose thereby using t...
ORGANISM(S): Lactobacillus plantarum 
2010-05-14 | E-GEOD-9392 | biostudies-arrayexpress
MetabolomicsDIVA Metabolomics: Differentiating Vaccination Status Following Viral Challenge Using Metabolomic Profiles
This study employed metabolomic profiling technologies, to identify metabolites (small molecules) in blood which are found at different levels in vaccinated compared to non-vaccinated animals exposed to virus.
2018-07-13 | MTBLS456 | MetaboLights
TranscriptomicsBatch wt vs hyper +_- pABA Normal int_Filtered fg-bg2
Transcriptional analysis upon the overexpression of the folate gene cluster on a high copy plasmid when compared to an empty vector in the lactic acid bacterium L. plantarum. The transcriptional response was determined for both strains in the presence and absence of pABA thereby using the hybridisat...
ORGANISM(S): Lactobacillus plantarum 
2008-05-31 | E-GEOD-8956 | biostudies-arrayexpress
MetabolomicsMetabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease

BACKGROUND: One-third of inflammatory bowel disease (IBD) patients show no response to infliximab (IFX) induction therapy, and approximately half of patients responding become unresponsive over time. Thus, identification of potential treatment response biomarkers are of great cl...

2022-01-13 | MTBLS239 | MetaboLights
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