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ProteomicsHuman holo-transferrin glycation
Understanding the effect of glycation on the function of transferrin, the systemic iron transporter, is fundamental to fully grasp the mechanisms leading to the loss of iron homeostasis observed in diabetes mellitus (DM). The spontaneous reaction with protein amino groups is one of the main causes o...
ORGANISM(S): Homo sapiens (Human) 
2018-05-30 | PXD009345 | Pride
Post-translational modification Holo-transferrin Blood serum Glycation Lc-ms/ms 
UnknownExtraintestinal pathogenic Escherichia coli utilizes the surface-expressed elongation factor Tu to bind and acquire iron from holo-transferrin.
Not available
S-EPMC9037478 | biostudies-literature
UnknownX-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin.
Not available
S-EPMC8705962 | biostudies-literature
UnknownApo- and holo-transferrin differentially interact with hephaestin and ferroportin in a novel mechanism of cellular iron release regulation.
Not available
S-EPMC10243088 | biostudies-literature
UnknownExtraintestinal Pathogenic Escherichia coli Utilizes Surface-Located Elongation Factor G to Acquire Iron from Holo-Transferrin.
Not available
S-EPMC9045202 | biostudies-literature
UnknownApo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier.
Not available
S-EPMC9882075 | biostudies-literature
UnknownAmyloid-β exposed astrocytes induce iron transport from endothelial cells at the blood-brain barrier by altering the ratio of apo- and holo-transferrin.
Not available
S-EPMC10592116 | biostudies-literature
TranscriptomicsTranscription profiling of T. brucei bloodstream forms cultured in different proportions of fetal bovine serum to investigate iron-sensing mechanisms
Bloodstream trypanosomes are sensitive to iron starvation, and upregulate ESAG6/7 transferrin receptor (TfR) mRNA and protein levels when placed in low transferrin or iron-depleted media, and adjust TfR expression to compensate for reduced endocytosis. Both observations suggest a specific transcript...
ORGANISM(S): Trypanosoma brucei 
2008-06-26 | E-MEXP-1530 | biostudies-arrayexpress
UnknownDetermination of LMF binding site on a HSA-PPIX complex in the presence of human holo transferrin from the viewpoint of drug loading on proteins.
Not available
S-EPMC3879261 | biostudies-literature
UnknownUse of spectroscopic, zeta potential and molecular dynamic techniques to study the interaction between human holo-transferrin and two antagonist drugs: comparison of binary and ternary systems.
Not available
S-EPMC6268275 | biostudies-literature
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