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TranscriptomicsDiscovery of the genes controlled by the second messenger cyclic di-GMP in Mycobacterium tuberculosis
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many biological processes in bacteria. The genome in Mycobacterium tuberculosis encodes a single copy of the diguanylate cyclase gene (dgc) responsible for c-di-GMP synthesis. To determine the role of c-di-GMP signaling in M. t...
ORGANISM(S): Mycobacterium tuberculosis 
2013-10-09 | E-GEOD-37973 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat model of hypertension kidney reveals gender-selective responses to salt in Dahl-Iwai and Sprague-Dawley strains
Dahl-Iwai (DI) salt-sensitive rats were studied using microarrays to identify gender-specific differences in the kidney, both basal differences and responses to a high salt diet. In DI rat kidneys, gene expression profiles demonstrated inflammatory and fibrotic responses selectively in females. Gona...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5285 | biostudies-arrayexpress
UnknownEchinacoside reduces intracellular c-di-GMP levels and potentiates tobramycin activity against Pseudomonas aeruginosa biofilm aggregates.
Not available
S-EPMC11889090 | biostudies-literature
UnknownUnusual reaction of (E)-2-[(benzo[d]thia-zol-2-yl-imino)-meth-yl]-5-(di-ethyl-amino)-phenol with tri-phenyl-borane: crystal structures and optical properties.
Not available
S-EPMC10626958 | biostudies-literature
Unknownc-di-GMP inhibits rRNA methylation and impairs ribosome assembly in the presence of kanamycin
Not available
S-SCDT-10_1038-S44319-025-00377-W | biostudies-other
ProteomicsAn Anti-Cancer Gold(III)-Activated Porphyrin Scaffold that Covalently Modifies Protein Cysteine Thiols
Cysteine thiols of many cancer-associated proteins are attractive targets of anti-cancer agents. Herein, we unequivocally demonstrate a distinct thiol-targeting property of gold(III) mesoporphyrin IX dimethyl ester (AuMesoIX) and its anti-cancer activities. While the binding of cysteine thiols with ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016875 | Pride
Gold • porphyrin • ligand reactivity• cysteine thiol conjugation • anti-tumor agents 
TranscriptomicsTranscriptome analysis of lungs from six different mouse strains after infection with highly pathogenic H5N1 influenza A virus [set 2]
Susceptible (DBA/2J, 129/SvImJ, A/J) and Resistant (SM/J, C57BL/6J, Balb/cJ) mouse strain were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 72 hours or not infected (control animals). Differences in expression were analyzed and used to identify candidate gen...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-64799 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of lungs from six different mouse strains after infection with highly pathogenic H5N1 influenza A virus [set 1]
Susceptible (DBA/2J, 129/SvImJ, A/J) and Resistant (SM/J, C57BL/6J, Balb/cJ) mouse strain were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 24 and 168 hours. Uninfected control animals were included. Differences in expression were analyzed and used to identi...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-64798 | biostudies-arrayexpress
UnknownAntioxidant and Cytoprotective Effects of the Di-O-Caffeoylquinic Acid Family: The Mechanism, Structure-Activity Relationship, and Conformational Effect.
Not available
S-EPMC6017143 | biostudies-literature
TranscriptomicsTranscriptome sequencing on a time series of potato infected with Globodera pallida to explore the sex determination
We explored the sex determination of Globodera pallida. To do so, we grew cuttings of the potato cultivar Desiree on Gamborg B5 medium supplemented with either 1.5 g/L or 20 g/L sucrose. 14-day-old cuttings were inoculated with 100 G. pallida E400 Rookmaker juveniles. Infected root tissue was harves...
ORGANISM(S): Globodera pallida 
2025-11-25 | E-MTAB-16117 | biostudies-arrayexpress
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