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Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights

Antimicrobial resistance (AMR) is one of the most urgent challenges in public health, and the horizontal transfer of antibiotic resistance genes (ARGs) mediated by mobile genetic elements (MGEs) drives its widespread global dissemination. Although integrative conjugative elements (ICEs) outnumber...

2025-10-15 | MTBLS13146 | MetaboLights
Comparison of gene content between R. solanacearum strains GMI1000, NCPPB332, GMI1000::NCPPB332 recombinants, CFBP2968 and GMI1000::CFBP2968 recombinants
ORGANISM(S): Ralstonia solanacearum 
Removing cellular transfer RNAs (tRNAs), making their cognate codons unreadable, creates a genetic firewall that prevents viral replication and horizontal gene transfer. However, numerous viruses and mobile genetic elements encode parts of the translational apparatus, including tRNAs, potentially re...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2022-07-08 | MSV000089854 | MassIVE
Extracellular vesicles (EVs) are central components of bacterial secretomes, including the small, cell wall-less Mollicutes. Although EV release in Mollicutes has been reported, EV proteomic composition and function have not been explored yet. We developed a protocol for isolating EVs of the pathog...
ORGANISM(S): Mycoplasmopsis bovis Mycoplasma mycoides 
2025-05-07 | PXD061464 | Pride
Vertical and horizontal gene transfer tradeoffs direct plasmid fitness
The rapid pace of evolution in bacteria is widely attributed to the promiscuous horizontal transfer and recombination of protein-coding genes. However, it is not known whether the same forces also drive the evolution of non-coding regulatory regions. Here we demonstrate that regulatory region can M-...
ORGANISM(S): Escherichia coli CFT073 
Experimental horizontal gene transfer in Vibrio cholerae
We evolved E. coli populations conjugating to DNA donors of different E. coli strains to novel nutrients to investigate the effects of horizontal gene transfer in adaptation.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Agrobacterium tumefaciens 
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