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TranscriptomicsImmunoregulatory actions of T cell PPAR g at the colonic mucosa
BACKGROUND: Peroxisome proliferator-activated receptor g (PPAR g) is a nuclear receptor whose activation has been shown to modulate macrophage and epithelial cell-mediated inflammation. The objective of this study was to use a systems approach for investigating the mechanism by which the deletion o...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-20523 | biostudies-arrayexpress
TranscriptomicsImmunoregulatory actions of epithelial cell PPAR g at the colonic mucosa
BACKGROUND: Peroxisome proliferator-activated receptor g (PPAR g) is a nuclear receptor whose activation has been shown to modulate macrophage and epithelial cell-mediated inflammation. The objective of this study was to use a systems approach for investigating the mechanism by which the deletion o...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-20621 | biostudies-arrayexpress
TranscriptomicsThe immunoregulatory effect of macrophage-specific PPAR gamma deficiency on experimental inflammatory bowel disease
Inflammatory bowel disease (IBD) is a condition characterized by severe intestinal inflammation and immune cell activation. The severity of the disease can be mitigated by compounds which activate peroxisome proliferator-activated receptor gamma (PPAR gamma), a receptor present widely in tissues in...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-23421 | biostudies-arrayexpress
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