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Transcriptomicsc-Myb inhibits myoblast fusion
The study of the effects of modification of c-Myb expression on differenatiation of C2C12 cells
ORGANISM(S): Mus musculus 
2013-10-21 | E-MTAB-1376 | biostudies-arrayexpress
TranscriptomicsGermination of Leafy Spurge (Euphorbia esula) Seeds under Constant and Alternating Temperature
Transcriptome changes were investigated for Euphorbia esula (leafy spurge) seeds with a focus on the effect of constant and diurnal fluctuating temperature on dormancy and germination. Leafy spurge seeds do not germinate when incubated for 21 days at 20°C constant temperatures, but nearly 30% germin...
ORGANISM(S): Euphorbia esula 
2010-06-01 | E-GEOD-18533 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of parotid tissue from Primary Sjögren’s Syndrome and controls
Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease with complex etiopathogenesis. Here we use Affymetrix U133 plus 2.0 microarray gene expression data from human parotid tissue. Parotid gland tissues were harvested from 17 pSS and 14 14 non-pSS sicca patients and 18 controls. The data ...
ORGANISM(S): Homo sapiens 
2012-09-06 | E-GEOD-40611 | biostudies-arrayexpress
ProteomicsMetabolic shift underlies recovery in reversible infantile respiratory chain deficiency
Reversible infantile respiratory chain deficiency (RIRCD) is a rare mitochondrial myopathy leading to severe metabolic disturbances in infants, which recover spontaneously after 6 months of age. RIRCD is associated with the homoplasmic m.14674T>C mitochondrial DNA mutation, however only ~1/100 carri...
ORGANISM(S): Homo sapiens (Human) 
2020-10-13 | PXD020181 | Pride
Mitochondrial myopathy Digenic inheritance Reversible infantile respiratory chain deficiency Homoplasmic trna mutation 
TranscriptomicsRole of the reprogramming factors in inducing pluripotency
Induced pluripotent stem (iPS) cells can be obtained from fibroblasts by expression of Oct4, Sox2, Klf4, and c-Myc. To determine how these factors induce this change in cell identity, we carried out genomewide promoter analysis of their binding in iPS and partially reprogrammed cells. Most targets i...
ORGANISM(S): Mus musculus 
2010-05-06 | E-GEOD-14012 | biostudies-arrayexpress
Unknownc-Myb inhibits myoblast fusion.
Not available
S-EPMC3804598 | biostudies-literature
UnknownEthyl EPA and ethyl DHA cause similar and differential changes in plasma lipid concentrations and lipid metabolism in subjects with low-grade chronic inflammation.
Not available
S-EPMC11836722 | biostudies-literature
TranscriptomicsBlood DNA methylation profiles in a Dutch population
Genome wide DNA methylation profiling of whole blood in schizophrenia patients and healthy subjects of different ages. The Illumina Infinium 450k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 480,000 CpGs. Dataset included 62 schizophrenia patie...
ORGANISM(S): Homo sapiens 
2012-10-19 | E-GEOD-41169 | biostudies-arrayexpress
UnknownRNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.
Not available
S-EPMC5989757 | biostudies-literature
TranscriptomicsDNA methylation profiles of human blood samples from a severe developmental disorder and controls
Human DNA methylation Beadchip v1.2 was used to obtain n=113 Illumina DNA methylation array from whole blood samples. The main goal of the study was to measure the epigenetic age (also known as DNA methylation age) of subjects with a severe developmental disorder (known as syndrome X) and controls. ...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-64495 | biostudies-arrayexpress
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