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MetabolomicsHost-gut microbiota interactions shape parasite infections in farmed Atlantic salmon

Animals and their associated microbiota share long evolutionary histories. However, it is not always clear how host genotype and microbiota interact to affect phenotype. We applied a hologenomic approach to explore how host-microbiota interactions shape lifetime growth and parasite infection in f...

2024-01-24 | MTBLS8575 | MetaboLights
MetabolomicsHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...
2018-02-12 | MTBLS452 | MetaboLights
TranscriptomicsGene expression differences underlying genotype-by-genotype specificity in a host-parasite system
Expression of bumblebees (Bombus terrestris) from four colonies exposed to 3 different genotypes of the trypanosome parasite Crithidia bombi RNA from guts of exposed individuals. Sacrificed 18hr after exposure.
ORGANISM(S): Bombus terrestris 
2014-04-28 | E-GEOD-55035 | biostudies-arrayexpress
TranscriptomicsLeishmania major modulates autophagy in host macrophages during intracellular differentiation
Autophagy generally participates in innate immunity by elimination of intracellular pathogens. However, many of them developed successful strategies to counteract their autolysosomal digestion and lastly to exploit this catabolic cellular process. Protozoan parasites of the genus Leishmania are the ...
ORGANISM(S): Mus musculus 
2015-08-03 | E-GEOD-52624 | biostudies-arrayexpress
TranscriptomicsDual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm-mosquito interactions
Parasite biology, by its very nature, cannot be understood without integrating it with that of the host, nor can the host response be adequately explained without considering the activity of the parasite. However, due to experimental limitations, molecular studies of parasite-host systems have been ...
ORGANISM(S): Aedes aegypti 
2014-04-15 | E-GEOD-53664 | biostudies-arrayexpress
TranscriptomicsTranscriptomic dissection of host-parasite interactions reveals metabolic rewiring in hepatocytes infected with Plasmodium berghei GAPs
we perform RNA sequencing to characterize host and parasite transcriptomic changes in hepatocytes infected with Plasmodium berghei GAPs lacking either Stearoyl-CoA Desaturase (Scd) or Sporozoite Conserved Orthologous Transcript 1 (Scot1). Both knockouts elicit distinct host transcriptional responses...
ORGANISM(S): Plasmodium berghei 
2026-05-15 | E-MTAB-16953 | biostudies-arrayexpress
GenomicsIllumina Novaseq transcripts from Tritrichomonas foetus MDCK host-parasite interactions
Illumina Novaseq of RNA extracted from several washes from host-parasite interactions from T. foetus-MDCK experiments
PRJEB39464 | ENA
MetabolomicsThe gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
The gut microbiota plays an important role in parasite-host interactions and the induction of immune defense responses. Trichinella spiralis is an important zoonotic parasite that can directly or indirectly interact with the host in the gut. Changes in the gut microbiota following infection with T. ...
2023-08-07 | MTBLS7603 | MetaboLights
UnknownTargeted repression of Plasmodium apicortin by host microRNA impairs malaria parasite growth and invasion.
Not available
S-EPMC7286292 | biostudies-literature
Genomics
Studies on host-parasite interactions
PRJNA1366642 | ENA
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