Sort   by:  
 Page size 
ProteomicsComprehensive evaluation of cleavable bioorthogonal probes for site-specific O-GlcNAc proteomics
O-linked β-N-acetylglucosamine (O-GlcNAc) modification (i.e., O-GlcNAcylation) on proteins is an essential modification in physiology and pathology. Although O-GlcNAcylation is functionally critical, its analysis has never been an easy task. Despite the existence of a number of methods developed in ...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-20 | PXD063995 | Pride
Mouse brain O-glcnac Click chemistry Lc-ms/ms 
ProteomicsA ROS-mediated Oxidation-O-GlcNAcylation cascade governs ferroptosis
Reactive oxygen species (ROS) play a crucial role in lipid peroxidation and the initiation of ferroptosis, significantly affecting chemotherapeutic drug resistance. However, the mechanisms by which ROS function and are sensed remain poorly understood. In this study, we identified O-GlcNAc transferas...
ORGANISM(S): Homo sapiens (Human) 
2025-05-28 | PXD064117 | Pride
Human Ogt Foxk2 Lc-ms/ms 
ProteomicsComparison of affinity enrichment methods for O-GlcNAc proteomics
In this work, by using the lysates of PANC-1 (a pancreatic cancer cell line), we provided a head-to-head comparison of three affinity enrichment methods/materials (i.e., antibody, lectin AANL6, and an OGA mutant) for O-GlcNAc proteomics. The enrichment was performed before or after high-pH HPLC frac...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Saccharomyces Cerevisiae (ncbitaxon:4932) 
2024-04-23 | MSV000094604 | MassIVE
ProteomicsLongitudinal Analysis of the Lung Proteome Reveals Persistent Repair Months after Mild to Moderate COVID-19
In order to assess the restoration of homeostasis in the lung proteome after COVID-19 infection, we performed bronchoalveolar lavage on 45 patients with mild to moderate disease at three phases (acute, recovery, convalescence) over a year. Changes in proteins were assessed using a multimodal approac...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-30 | MSV000094898 | MassIVE
Sort   by:  
 Page size