Ogt - OmicsDI

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Homo sapiens (73)
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Metabolite Name

DTDP-4-acetamido-4,6-dideoxy-D-galactose (1)
P-Acetamidophenol (Acetaminophen, Tylenol) (1)
(S)-2-Hydroxy-2-phenylacetonitrile O-b-D-allopyranoside (1)
4,6,7-trihydroxy-2H-chromen-2-one (1)
5,7-Dihydroxy-4'-methoxy-8-methylflavanone (1)
Cis-Resveratrol 3-O-glucuronide (1)
4-{[3-(hydroxymethyl)-3-methyloxiran-2-yl]methoxy}-7H-furo[3,2-g]chromen-7-one (1)
8-(1-hydroxy-2-methoxypropan-2-yl)-2H-furo[2,3-h]chromen-2-one (1)
5-Aminosalicylic??acid (1)
FA(18:2(OH3)) (1)
FA(18:2(OH2)) (1)
FA(18:1(OH1)) (1)
(¡À)-Enterolactone (1)
PS(15:0/18:1(11Z)) (1)
L-alpha-Phosphatidylethanolamine (1)
Y-Linolenic acid (1)
Abu-Trp-OH (1)
FA(12:1(OH1)) (1)
1-(4-methoxy-1-benzofuran-5-yl)ethan-1-one (1)
Ethyl (2E)-3-(4-hydroxyphenyl)prop-2-enoate (1)
[(3-methylbut-2-en-1-yl)oxy]sulfonic acid (1)
Cinchonain Id 7-glucoside (1)
2-{[(2,4-dihydroxy-5-methoxyphenyl)(hydroxy)methylidene]amino}acetic acid (1)
Cis-6-Nitro-p-mentha-1(7),2-diene (1)
Beta-D-Xylopyranosyl-(1->5)-alpha-L-arabinofuranosyl-(1->5)-L-arabinose (1)
Cis-10-Hydroxylinalyl oxide 7-glucoside (1)
FA(18:1(OH3)) (1)
Methyl (2R*,3S*)-2,3-dihydro-3-hydroxy-2-isopropenyl-5-benzofurancarboxylate (1)
Cis-4-Hydroxycyclohexylacetic acid (1)
Isokaempferide (1)

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bacteria (2)

Study type

Transcription profiling by array (20)
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Lab affiliation

Peking University (3)
college of pharmacy, Nankai university,Tianjin, 300353, China (2)
Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No.218 Jixi Road, Hefei 230022, China (2)
George Washington University (2)
College of Chemistry and Molecular Engineering, Peking University, Beijing, China. (2)
Carnegie MS facility (2)
Department of Biochemistry and Molecular Biology, Drexel University College of Medicine. Translational Cellular Oncology Program, Sidney Kimmel Cancer Center, Thomas Jefferson University (1)
State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing 100101, China (1)
The Johns Hopkins University, School of Medicine. The Department of Biological Chemistry. (1)
The Department of Biological Chemistry, The Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205-2185, USA, Telephone: (410) 955-7049; Fax: (410) 955-5759 (1)
Dana Farber Cancer Institute, Dept. Cancer Biology; Harvard Medical Schoool, Dept. Cell Biology (1)
Southern medical university,China (1)
CARNEGIE MS FACILITY (1)
Department of Molecular Genetics and Cell Biology and Ludwig Center for Metastasis Research, The University of Chicago, Chicago IL (1)
Department of Molecular Biology and Genetics - Cellular Health, Intervention, and Nutrition, Aarhus University (1)
Associate Professor of Chemistry and Chemical Biology, DEPARTMENT of CHEMISTRY & CHEMICAL BIOLOGY, HARVARD UNIVERSITY (1)
Associate Professor of Chemistry and Chemical Biology Department of Chemistry and Chemical Biology Harvard University, USA (1)
Department of Microbiology, Blavatnik Institue of Harvard Medical School (1)
Max Planck Institute of Biochemistry Am Klopferspitz 18, 82152 Planegg (1)
Telethon Institute of Genetics and Medicine, Pozzuoli, Italy (1)
Department of Biological Chemistry The Johns Hopkins School of Medicine Baltimore, MD, 21205, USA (1)
Beijing Key Laboratory of DNA Damage Response and College of Life Sciences, Capital Normal University, Beijing 100048, China (1)
1Department of Pathology; University of California San Diego; La Jolla, CA 92093; USA (1)
Milton and Rosalind Chang Professor of Chemistry, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA (1)
Georgetown University (1)
University of Copenhagen Faculty of Health Sciences Centre for Glycomics Department of Cellular and Molecular Medicine Copenhagen Denmark (1)
Lab head (1)
Key Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, 5268 Renmin Street, Changchun, Jilin, 130024, China (1)
Dana-Farber Cancer Institute, Dept. Cancer Biology; Harvard Medical School, Dept. Cell Biology (1)
Beijing Key Laboratory of DNA Damage Response and College of Life Science, Capital Normal University, Beijing 100048, China (1)

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Ogt chromatin recruitment is mediated by TET proteins in mouse ES cells [ChIP-Seq]

These data include the genome wide location analysis of Ogt by ChIP of Ogt in mouse ES cells. Precipitation of formaldehyde cross-linked chromatin prepared from mouse ES cell using specific antibody against OGT and IgG as control.

ORGANISM(S): Mus musculus

2013-01-06 | E-GEOD-39154 | biostudies-arrayexpress

OGT controls mammalian cell viability by regulating the proteasome/mTOR/mitochondrial axis

TMT-based proteomic and phosphoproteomic analysis of mouse embryonic stem cells upon deletion of Ogt.

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

2021-11-16 | MSV000088393 | MassIVE

OGT, H2B S112GlcNAc, TET2 ChIP-seq results

TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interaction does not regulate the enzymatic activity of TET2, it facilitates OGT-dependent histone O-GlcNAcylation. Moreover, OGT associates with TET2 at transcription starting s...

ORGANISM(S): Mus musculus

2012-12-11 | E-GEOD-41720 | biostudies-arrayexpress

Quantitative Proteomics Reveals that the OGT Interactome is Remodeled in Response to Oxidative Stress

The dynamic modification of specific serine and threonine residues of intracellular proteins by O-linked N-acetyl-β-D-glucosamine (O-GlcNAc) mitigates injury and promotes cytoprotection in a variety of stress models. The O-GlcNAc transferase (OGT) and the O-GlcNAcase (OGA) are the sole enzymes that ...

ORGANISM(S): Mus Musculus

2021-04-05 | PXD021091 | panorama

Genome wide binding sites of BAP1, HCF1 and OGT

We report the genome wide binding sites of BAP1, HCF1 and OGT in bone marrow derived macrophages. De-ubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with increased risk of mesothelioma and uveal melanoma. Somatic BAP1 mutations occur in various malignancies. We show that mouse ...

ORGANISM(S): Mus musculus

2012-11-07 | E-GEOD-40723 | biostudies-arrayexpress

The ubiquitin E3 ligase APC/CCdc20 mediates mitotic degradation of OGT

O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is the sole enzyme that catalyzes all O-GlcNAcylation reactions intracellularly. Previous investigations have found that OGT levels oscillate during the cell division process. Specifically, OGT abundance is downregulated during mitosis, but...

ORGANISM(S): Homo sapiens (Human)

2024-08-10 | PXD050552 | Pride

Total RNA-seq upon degradation of OGT by siRNA

Evaluation of change in gene expression upon degradation of OGT by siRNA

ORGANISM(S): Mus musculus

2024-08-31 | E-MTAB-14313 | biostudies-arrayexpress

A ROS-mediated Oxidation-O-GlcNAcylation cascade governs ferroptosis

Reactive oxygen species (ROS) play a crucial role in lipid peroxidation and the initiation of ferroptosis, significantly affecting chemotherapeutic drug resistance. However, the mechanisms by which ROS function and are sensed remain poorly understood. In this study, we identified O-GlcNAc transferas...

ORGANISM(S): Homo sapiens (Human)

2025-05-28 | PXD064117 | Pride

Human Ogt Foxk2 Lc-ms/ms

OGT knockout S2VP10 cells

PRJNA471509 | ENA

Expression data from ES cells

ORGANISM(S): Mus musculus

2012-12-11 | E-GEOD-41721 | biostudies-arrayexpress

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