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ProteomicsLC–MS/MS Proteomic Profiling of PEAK3 S69 Phosphorylation in PEAK3 Mutants
This project aims to investigate how different PEAK3 mutations affect phosphorylation at serine 69 (S69). To this end, we performed proteomic analyses on immunoprecipitated (IP) PEAK3 samples from both wild-type and mutant constructs. Peptides containing phosphorylated and non-phosphorylated S69 wer...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD071947 | Pride
Proteomics Peak3 Breast cancer Lc-ms/ms 
ProteomicsLC-MSMS based (phospho)proteomics on gastric cancer cell lines
We exploit a large panel of gastric cancer cell lines and three powerful (phospho)proteomic workflows, including tyrosine phosphorylation profiling, to provide the characterization of the gastric cancer proteome. The resulting datasets are used individually and in an integrated manner to generate no...
ORGANISM(S): Homo sapiens (Human) 
2024-12-16 | PXD048538 | Pride
Lc-msms Proteomics Gastric cancer Tyrosine phosphorylation profiling Phosphoproteomics 
ProteomicsPhosphoproteomics Reveals EPHA2 and EGFR Activation Following Wnt Pathway Inhibition in Wnt-Driven Tumours
Wnt signalling represses multiple receptor tyrosine kinases (RTKs) in Wnt-high cancers. To identify RTKs responsible for MAPK activation following Wnt pathway inhibition, phosphotyrosine-targeted mass spectrometry was performed on xenograft tumour samples derived from HPAF-II and HCT116 cells. Tumou...
ORGANISM(S): Homo sapiens (Human) 
2026-08-20 | PXD079682 | Pride
Wnt signalling Epha2 Phosphoproteomics Egfr Immunoprecipitation-mass spectrometry Lc-ms/ms 
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