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ProteomicsModerate-Intensity Interval Exercise Exacerbates Cardiac Lipotoxicity in High-Fat, High-Calories Diet-Fed Mice
Physical exercise is a cornerstone for preventing diet-induced obesity, while it is unclear whether physical exercise could offset high-fat, high-calories diet (HFCD)-induced cardiac dysfunction. Here, mice were fed with HFCD and simultaneously subjected to physical exercise. As expected, physical e...
ORGANISM(S): Mus Musculus 
2024-11-30 | PXD058460 |
MetabolomicsPyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart

Increased protein acetylation is frequently observed in the failing heart, including in hearts with heart failure with preserved ejection fraction (HFpEF). However, the role of protein acetylation in cardiac metabolic impairments during the pathogenesis of HFpEF remains insufficiently investigate...

2025-09-01 | MTBLS12919 | MetaboLights
UnknownMolecular cytogenetic (FISH) and genome analysis of diploid wheatgrasses and their phylogenetic relationship.
Not available
S-EPMC5344461 | biostudies-literature
UnknownDeveloping a crisis leadership evaluation system for Chinese nursing staff during major infectious disease emergencies: a modified Delphi study.
Not available
S-EPMC12312600 | biostudies-literature
ProteomicsPhosphoproteomics reveals key regulatory kinases and modulated pathways involved in tumorigenesis of ovarian cancer
The present study comprehensively revealed the molecular characteristics in relation to OC and identified significantly distinct phosphorylated sites and phosphorylated proteins underlying the syndrome. The results here dissected regulatory elements (especially kinases) and pathways involved in canc...
ORGANISM(S): Homo Sapiens 
2019-12-31 | PXD016183 |
UnknownParkinsonism and dysautonomia with anti-CV2/CRMP5 associated paraneoplastic neurological syndromes mimicking multiple system atrophy: a case report.
Not available
S-EPMC8547084 | biostudies-literature
ProteomicsPyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
Increased protein acetylation is frequently observed in the failing heart, including in hearts with heart failure with preserved ejection fraction (HFpEF). However, the role of protein acetylation in cardiac metabolic impairments during the pathogenesis of HFpEF remains insufficiently investigated. ...
ORGANISM(S): Mus Musculus 
2025-09-11 | PXD068270 |
UnknownSKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1.
Not available
S-EPMC7713163 | biostudies-literature
UnknownThe relative and combined ability of triglyceride-glucose index and stress hyperglycemia ratio to predict major adverse cardio-cerebral events in patients with multivessel coronary artery disease.
Not available
S-EPMC11437960 | biostudies-literature
UnknownSpecific Strains of Honeybee Gut Lactobacillus Stimulate Host Immune System to Protect against Pathogenic Hafnia alvei.
Not available
S-EPMC8729767 | biostudies-literature
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