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TranscriptomicsDynamic transcriptomes of human myeloid leukemia cells
To identify the mechanisms controlling chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) in humans, we analyzed genome-wide transcription dynamics in three myeloid leukemia cell lines (K562, HL-60, and THP1) using high-throughput sequencing technology. Using KEGG analysis, we found tha...
ORGANISM(S): Homo sapiens 
2013-10-09 | E-GEOD-46164 | biostudies-arrayexpress
TranscriptomicsTranscriptomes of K562 cell line
To investigate the expression level of genes in K562 cells Profiling the transcriptome of K562
ORGANISM(S): Homo sapiens 
2013-07-15 | E-GEOD-39374 | biostudies-arrayexpress
TranscriptomicsCharacterization of miRNomes in acute and chronic myeloid leukemia cells
An in-depth analysis of miRNomes in 3 human myeloid leukemia cell lines was carried out to comprehensively identify miRNAs that distinguish acute and chronic myeloid leukemias and relate to myeloid cell differentiation. Characterization the miRNomes in 3 myeloid leukemia cell lines.
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-48059 | biostudies-arrayexpress
TranscriptomicsDynamic transcriptomes during human erythroid differentiation and development
To explore the mechanisms controlling erythroid differentiation and development in human, we analyzed the genome-wide transcription dynamics that occurs during the differentiation of HESCs into the erythroid lineage and development of embryonic to adult erythropoiesis using high throughput sequencin...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-32991 | biostudies-arrayexpress
TranscriptomicsWhole Transcriptome RNA-seq Analysis: the Tumorigenesis and Metastasis of Melanoma
To better understand the tumorigenesis and metastasis of human metastatic melanoma(MM) , we analyzed the transcriptomes of three cell lines that represent the three distinct stages of MM pathogenesis: the normal stage (HEMn), the onset of MM (A375), and the metastasis stage (A2085). Using the next g...
ORGANISM(S): Homo sapiens 
2015-02-10 | E-GEOD-35704 | biostudies-arrayexpress
TranscriptomicsProtein arginine methyltransferase AtPRMT5 is involved in pre-mRNA splicing in Arabidopsis thaliana
In this study, we analyzed the Arabidopsis homologue of PRMT5, AtPRMT5M-bM-^@M-^Ys function in RNA processing. RNA-seq analyses revealed that AtPRMT5 is involved in a subset of pre-mRNA splicing. Several RNA processing factors involved in regulating flowering time were validated that the correspondi...
ORGANISM(S): Arabidopsis thaliana 
2010-10-07 | E-GEOD-21323 | biostudies-arrayexpress
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