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TranscriptomicsTranscription profiling of blasts from three APL patients expressing PML/RAR before and after treatment with 1 uM retinoic acid (RA) in vitro for four hours
Gene expression profiles in blasts from three APL patients expressing PML/RAR were assessed before and after treatment with 1 uM retinoic acid (RA) in vitro for four hours. We then studied a U937 clone conditionally expressing PML/RAR (U937-PR), (Grignani et al. 1993) (Alcalay et al. 2003), and comp...
ORGANISM(S): Homo sapiens 
2004-12-31 | E-MEXP-149 | biostudies-arrayexpress
ProteomicsOmics Reveal Far Reaching Effects of Verapamil Treatment in Subjects with Type 1 Diabetes
Proteomic data from recent onset T1D patients treated with verapamil where significant extension of the honeymoon phase was observed. Samples were depleted with MARS Hu-14 column, digested with trypsin, labeled with 11-plex TMT, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-09 | MSV000087598 | MassIVE
TranscriptomicsFoxp1 is a rate-limiting and essential negative regulator of Tfh cell differentiation
CD4+ T follicular helper (Tfh) cells are essential for germinal center (GC) and high-affinity antibody responses. Yet the regulation that determines the initial development of Tfh cells is still largely unknown. Here we find that transcription factor Foxp1, previously shown to be essential in mainta...
ORGANISM(S): Mus musculus 
2014-05-18 | E-GEOD-50725 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of dissected neuroepithelium (Neur.) and from all other non-neuroepithelial tissues (N. Neur for Non Neuronal tissues) from six wild type (WT) and six Mdm4-null mouse embryos (KO)
Total RNA was isolated from the dissected neuroepithelium (Neur.) and from all other non-neuroepithelial tissues (N. Neur for Non Neuronal tissues) from six wild-type (WT) and six Mdm4-null embryos (KO). Equal quantities of total RNA from single samples were used to obtain four RNA pools (WT-Neur, W...
ORGANISM(S): Mus musculus 
2004-12-31 | E-MEXP-155 | biostudies-arrayexpress
UnknownRhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.
Not available
S-EPMC122231 | biostudies-literature
UnknownProtocol and Statistical Analysis Plan for the Vasopressin for Septic Shock Pragmatic (VASSPR) Cluster-Crossover Randomized Trial.
Not available
S-EPMC12810988 | biostudies-literature
UnknownPenetrative biomimetic nanovehicle boosts immunotherapy in triple-negative breast cancer via SOS1 blockade.
Not available
S-EPMC12482630 | biostudies-literature
UnknownTherapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.
Not available
S-EPMC6988856 | biostudies-literature
UnknownInternal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Not available
S-EPMC9847506 | biostudies-literature
UnknownTP53 mutation detected in circulating exosomal DNA is associated with prognosis of patients with hepatocellular carcinoma.
Not available
S-EPMC9354767 | biostudies-literature
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