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ProteomicsRat hippocampal neurons' proteomes
We induced over-expression and under-expression of Camk2b in cultured rat hippocampal neurons through transfection with lentivirus plasmids. Then isobaric tag for relative and absolute quantitation (iTRAQ)-based quantitative proteomics followed by bioinformatics analyses were carried out to explore...
ORGANISM(S): Rattus Norvegicus 
2022-07-27 | PXD033931 |
ProteomicsHippocampal proteomics of CMS-treated rats
We used a chronic mild stress (CMS) protocol to separate susceptible-depression, susceptible-anxiety and insusceptible rat subgroups. Differential proteomes in the hippocampus were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrometry...
ORGANISM(S): Rattus Norvegicus 
2019-10-21 | PXD015946 |
ProteomicsAnimal proteomics of depression
The amygdala plays a key role in the pathophysiology of depression, but the molecular mechanisms underlying amygdalar hyperactivity in depression remain unclear. In this study, we used a chronic mild stress (CMS) protocol to separate susceptible and insusceptible rat subgroups. Proteomes in the amyg...
ORGANISM(S): Rattus Norvegicus 
2019-01-15 | PXD044124 |
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