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ProteomicsA bioenergetic shift is required for spermatogonial differentiation
A bioenergetic balance between glycolysis and mitochondrial respiration is particularly important for stem cell fate specification. It however remains to be determined whether undifferentiated spermatogonia switch their preference of bioenergy production during differentiation. In this study, we fou...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD019136 | Pride
Spermatogonial differentiation Oxphos Glycolysis 
ProteomicsGlucosidase Alpha Neutral C Promotes Influenza Virus Replication by Inhibiting Proteosome-Dependent Degradation of Hemagglutinin
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into the role of glucosidase alpha, neutral C (ganc) gene in human H7N9 infections. Through whole gen...
ORGANISM(S): Homo Sapiens 
2025-03-10 | PXD061732 |
Proteomicsidentification of ECE1-interacting proteins
LN229 cells were subjected to Co-IP using IgG and anti-ECE1 antibodies. The immunoprecipitated complexes were validated by Western blot and subsequently analyzed by liquid chromatography–mass spectrometry (HPLC-MS/MS, QLBio, China) for identification of ECE1-interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD071913 | Pride
Ece1 
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