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ProteomicsPhosphoproteomic analysis reveals Rio1 regulated protein metabolism in response to UV irradiation and multiple cellular processes in Sulfolobus islandicus REY15A
In this study, we performed quantitative phosphoproteomic analysis on S. islandicus REY15A either treated with UV or in the absence of Rio1.
ORGANISM(S): Sulfolobus islandicus REY15A 
2020-11-05 | PXD021663 | Pride
Phosphoproteome Archaea Rio Uv irradiation Protein phosphorylation Sulfolobus islandicus 
TranscriptomicsGenomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant–Mediated Nephrotoxicity
The use of calcineurin inhibitor (CI) immunosuppressants has significantly improved the early allograft survival rate in organ transplantation. However, CI therapy has been associated with chronic nephrotoxicity, which limits their long-term utility. In order to understand the mechanisms of the toxi...
ORGANISM(S): Rattus norvegicus 
2011-11-23 | E-GEOD-19366 | biostudies-arrayexpress
ProteomicsQuantitative Proteomics Reveal the Protective Effects of CuraUltra Against Alzheimer’s Disease via Modulating the Expression of Synapse-associated Proteins in Mouse Model
To identify the potential molecular mechanism responsible for the effect on CuraUltra treatment, label-free quantitative proteomics by tandem mass spectrometry (LC-MS / MS) were performed, which provides in depth characterization of protein profile changes . Critical altered proteins were validated ...
ORGANISM(S): Mus Musculus 
2021-11-10 | PXD029640 |
ProteomicsDiscovery of efficacy biomarkers for NSCLC with first-line anti-PD-1 immunotherapy by DIA
To discover potential plasma biomarkers, we are aiming to explore circulating and tumor-derived proteins related to the efficacy of anti-PD-1 treatment to select the optimal NSCLC patients for immunotherapy via DIA.
ORGANISM(S): Homo Sapiens 
2022-02-07 | PXD031474 |
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